Small cell lung cancer presenting as a paraneoplastic syndrome characterized by recurrent episodic hypotension and bradycardia

Mike G. Martin; Amer K. Ardati; Shannon M. Dunlay; Amy P. Abernethy; Michael A. Blazing

doi:10.1378/chest.06-1281

Small cell lung cancer presenting as a paraneoplastic syndrome characterized by recurrent episodic hypotension and bradycardia

Mike G. Martin, Amer K. Ardati, Shannon M. Dunlay, Amy P. Abernethy, Michael A. Blazing

Cardiovascular Medicine

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

A 56-year-old man presenting with a 6-month history of recurrent episodic hypotension and bradycardia was found to have limited-stage small cell lung cancer. During both quiescence and episodes of hemodynamic embarrassment, extensive evaluations were conducted. Possible explanations included the following: intermittent great vessel obstruction; baroreceptor failure/hypersensitivity; and autonomic dysfunction. His clinical course favored an antibody-negative dysautonomic paraneoplastic syndrome.

Original language	English (US)
Pages (from-to)	290-293
Number of pages	4
Journal	Chest
Volume	131
Issue number	1
DOIs	https://doi.org/10.1378/chest.06-1281
State	Published - Jan 2007

Keywords

Critical care
Hypotension
Lung cancer

ASJC Scopus subject areas

Pulmonary and Respiratory Medicine
Critical Care and Intensive Care Medicine
Cardiology and Cardiovascular Medicine

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10.1378/chest.06-1281

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abstract = "A 56-year-old man presenting with a 6-month history of recurrent episodic hypotension and bradycardia was found to have limited-stage small cell lung cancer. During both quiescence and episodes of hemodynamic embarrassment, extensive evaluations were conducted. Possible explanations included the following: intermittent great vessel obstruction; baroreceptor failure/hypersensitivity; and autonomic dysfunction. His clinical course favored an antibody-negative dysautonomic paraneoplastic syndrome.",

keywords = "Critical care, Hypotension, Lung cancer",

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AU - Dunlay, Shannon M.

AU - Abernethy, Amy P.

AU - Blazing, Michael A.

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AB - A 56-year-old man presenting with a 6-month history of recurrent episodic hypotension and bradycardia was found to have limited-stage small cell lung cancer. During both quiescence and episodes of hemodynamic embarrassment, extensive evaluations were conducted. Possible explanations included the following: intermittent great vessel obstruction; baroreceptor failure/hypersensitivity; and autonomic dysfunction. His clinical course favored an antibody-negative dysautonomic paraneoplastic syndrome.

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Small cell lung cancer presenting as a paraneoplastic syndrome characterized by recurrent episodic hypotension and bradycardia

Abstract

Keywords

ASJC Scopus subject areas

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