Small bowel transit and gastric emptying after biliodigestive anastomosis using the uncut jejunal loop

Alexander Klaus, Ronald A. Hinder, Justin H Nguyen, Kevin L. Nelson

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Background: The Roux-en-Y loop is an effective procedure for biliodigestive drainage. However, up to 15% of patients suffer from postoperative cholangitis or blind loop syndrome. A new technique to prevent motility abnormalities has been developed. Methods: Male Lewis rats were used to compare gastric emptying and transit in the small bowel after either a standard Roux-en-Y anastomosis or a new biliodigestive anastomosis technique which involves creating an "uncut" jejunal loop with luminal occlusion. Unoperated rats served as controls. 99Technetium HIDA and 111Indium-tagged amberlite were respectively used to investigate small bowel transit and gastric emptying. Results: Histopathology showed distinctive abnormalities only in the liver of conventional Roux-en-Y animals. No recanalization of the obliterated gut lumen occurred in uncut Roux animals. Distribution of 99Tc-HIDA and 111In showed were similar in both groups. Gastric emptying is slowed in both groups. Conclusions: The uncut proximal jejunum loop is a good alternative to the conventional Roux-en-Y loop and showed preserved small bowel motility and adequate jejunal transit. Gastric emptying is slowed in both groups.

Original languageEnglish (US)
Pages (from-to)747-751
Number of pages5
JournalAmerican Journal of Surgery
Volume186
Issue number6
DOIs
StatePublished - Dec 2003

Fingerprint

Roux-en-Y Anastomosis
Gastric Emptying
Blind Loop Syndrome
Cholangitis
Jejunum
Drainage
Liver
lidofenin

Keywords

  • Biliodigestive anastomosis
  • Cholangitis
  • Motility
  • Roux-en-Y

ASJC Scopus subject areas

  • Surgery

Cite this

Small bowel transit and gastric emptying after biliodigestive anastomosis using the uncut jejunal loop. / Klaus, Alexander; Hinder, Ronald A.; Nguyen, Justin H; Nelson, Kevin L.

In: American Journal of Surgery, Vol. 186, No. 6, 12.2003, p. 747-751.

Research output: Contribution to journalArticle

Klaus, Alexander ; Hinder, Ronald A. ; Nguyen, Justin H ; Nelson, Kevin L. / Small bowel transit and gastric emptying after biliodigestive anastomosis using the uncut jejunal loop. In: American Journal of Surgery. 2003 ; Vol. 186, No. 6. pp. 747-751.
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