Small bowel adenocarcinoma: A rare but aggressive disease

Thierry Delaunoit, Florence Neczyporenko, Paul John Limburg, Charles Erlichman

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Unlike the colon and rectum, the small intestine is associated with a very low rate of tumor occurrence. Adenocarcinomas represent the most frequent of these rare digestive tumors and are often fatal as a result of tardy diagnosis. Regardless of the stage, surgery usually remains the cornerstone of small bowel adenocarcinoma therapy. Because of the rarity of the disease, very few significant clinical trials have identified any efficient nonsurgical treatment; however, recent data indicate these tumors might be sensitive to chemotherapy alone or in association with radiation therapy. Conversely, a great deal of progress has been achieved in diagnosis of the tumor, whether by adaptation of existing techniques or development of new ones. We reviewed the clinical aspects of this rare but aggressive disease, focusing on new diagnostic procedures as well as on recent advances in their therapeutic management.

Original languageEnglish (US)
Pages (from-to)241-248
Number of pages8
JournalClinical Colorectal Cancer
Volume4
Issue number4
StatePublished - 2004

Fingerprint

Rare Diseases
Adenocarcinoma
Neoplasms
Rectum
Small Intestine
Colon
Radiotherapy
Therapeutics
Clinical Trials
Drug Therapy

Keywords

  • Drug therapy
  • Endoscopy
  • Intestinal neoplasms
  • Small intestine

ASJC Scopus subject areas

  • Oncology

Cite this

Delaunoit, T., Neczyporenko, F., Limburg, P. J., & Erlichman, C. (2004). Small bowel adenocarcinoma: A rare but aggressive disease. Clinical Colorectal Cancer, 4(4), 241-248.

Small bowel adenocarcinoma : A rare but aggressive disease. / Delaunoit, Thierry; Neczyporenko, Florence; Limburg, Paul John; Erlichman, Charles.

In: Clinical Colorectal Cancer, Vol. 4, No. 4, 2004, p. 241-248.

Research output: Contribution to journalArticle

Delaunoit, T, Neczyporenko, F, Limburg, PJ & Erlichman, C 2004, 'Small bowel adenocarcinoma: A rare but aggressive disease', Clinical Colorectal Cancer, vol. 4, no. 4, pp. 241-248.
Delaunoit T, Neczyporenko F, Limburg PJ, Erlichman C. Small bowel adenocarcinoma: A rare but aggressive disease. Clinical Colorectal Cancer. 2004;4(4):241-248.
Delaunoit, Thierry ; Neczyporenko, Florence ; Limburg, Paul John ; Erlichman, Charles. / Small bowel adenocarcinoma : A rare but aggressive disease. In: Clinical Colorectal Cancer. 2004 ; Vol. 4, No. 4. pp. 241-248.
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