Sleep apnea

Thomas Konecny; Virend Somers

doi:10.1016/B978-0-323-85492-4.00059-4

Sleep apnea

Thomas Konecny, Virend Somers

Cardiovascular Medicine

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Sleep apnea (obstructive and central) has been closely connected with adverse cardiovascular outcomes, and the autonomic nervous system may provide a key mechanistic link. Repetitive sleep apneas lead to profound and acute changes in both sympathetic and parasympathetic activation. Patients with frequent apneas may suffer from chronic adverse effects even during wakefulness. This chapter reviews autonomic mechanisms linking sleep apnea with cardiac arrhythmias, sudden death, hypertension, and heart failure, including exploration of their modifiable therapeutic potential.

Original language	English (US)
Title of host publication	Primer on the Autonomic Nervous System, Fourth Edition
Publisher	Elsevier
Pages	657-662
Number of pages	6
ISBN (Electronic)	9780323854924
ISBN (Print)	9780323854931
DOIs	https://doi.org/10.1016/B978-0-323-85492-4.00059-4
State	Published - Jan 1 2022

Keywords

Blood pressure
Central sleep apnea
Cheyne-Stokes respiration
Heart failure
Heart rate variability
Rapid eye movement
Sleep apnea

ASJC Scopus subject areas

General Medicine
General Neuroscience

Access to Document

10.1016/B978-0-323-85492-4.00059-4

Cite this

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AB - Sleep apnea (obstructive and central) has been closely connected with adverse cardiovascular outcomes, and the autonomic nervous system may provide a key mechanistic link. Repetitive sleep apneas lead to profound and acute changes in both sympathetic and parasympathetic activation. Patients with frequent apneas may suffer from chronic adverse effects even during wakefulness. This chapter reviews autonomic mechanisms linking sleep apnea with cardiac arrhythmias, sudden death, hypertension, and heart failure, including exploration of their modifiable therapeutic potential.

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KW - Cheyne-Stokes respiration

KW - Heart failure

KW - Heart rate variability

KW - Rapid eye movement

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BT - Primer on the Autonomic Nervous System, Fourth Edition

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ER -

Sleep apnea

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

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