Sleep apnea

Thomas Konecny, Virend Somers

Research output: Chapter in Book/Report/Conference proceedingChapter


Sleep apnea (obstructive and central) has been closely connected with adverse cardiovascular outcomes, and the autonomic nervous system may provide a key mechanistic link. Repetitive sleep apneas lead to profound and acute changes in both sympathetic and parasympathetic activation. Patients with frequent apneas may suffer from chronic adverse effects even during wakefulness. This chapter reviews autonomic mechanisms linking sleep apnea with cardiac arrhythmias, sudden death, hypertension, and heart failure, including exploration of their modifiable therapeutic potential.

Original languageEnglish (US)
Title of host publicationPrimer on the Autonomic Nervous System, Fourth Edition
Number of pages6
ISBN (Electronic)9780323854924
ISBN (Print)9780323854931
StatePublished - Jan 1 2022


  • Blood pressure
  • Central sleep apnea
  • Cheyne-Stokes respiration
  • Heart failure
  • Heart rate variability
  • Rapid eye movement
  • Sleep apnea

ASJC Scopus subject areas

  • Medicine(all)
  • Neuroscience(all)


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