Skeletal muscle tensile strain dependence: Hyperviscoelastic nonlinearity

Benjamin B. Wheatley, Duane A. Morrow, Gregory M. Odegard, Kenton R Kaufman, Tammy L. Haut Donahue

Research output: Contribution to journalArticle

21 Scopus citations

Abstract

Introduction: Computational modeling of skeletal muscle requires characterization at the tissue level. While most skeletal muscle studies focus on hyperelasticity, the goal of this study was to examine and model the nonlinear behavior of both time-independent and time-dependent properties of skeletal muscle as a function of strain. Materials and methods: Nine tibialis anterior muscles from New Zealand White rabbits were subject to five consecutive stress relaxation cycles of roughly 3% strain. Individual relaxation steps were fit with a three-term linear Prony series. Prony series coefficients and relaxation ratio were assessed for strain dependence using a general linear statistical model. A fully nonlinear constitutive model was employed to capture the strain dependence of both the viscoelastic and instantaneous components. Results: Instantaneous modulus (p0.1). Additionally, the fully nonlinear hyperviscoelastic constitutive model provided an excellent fit to experimental data, while other models which included linear components failed to capture muscle function as accurately. Conclusions: Material properties of skeletal muscle are strain-dependent at the tissue level. This strain dependence can be included in computational models of skeletal muscle performance with a fully nonlinear hyperviscoelastic model.

Original languageEnglish (US)
Article number1601
Pages (from-to)445-454
Number of pages10
JournalJournal of the Mechanical Behavior of Biomedical Materials
Volume53
DOIs
StatePublished - Jan 1 2016

ASJC Scopus subject areas

  • Biomaterials
  • Biomedical Engineering
  • Mechanics of Materials

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