Abstract
Background: Sinonasal adenocarcinoma (SNAC) is a rare tumor. The impact of health disparities on survival, stage at presentation, and utilization of surgery is not well understood in patients with SNAC. Methods: The Surveillance, Epidemiology, and End Results database was queried for cases of SNAC from 1973 to 2015. Cases were analyzed to assess for disparities in presentation, treatment, and survival. Results: SNAC was identified in 630 patients. In a multivariate model of overall survival, an age increase of 10 years (Hazard Ratio (HR) = 1.37, p < 0.001), male sex (HR = 1.26, p = 0.045), and more recent decade of diagnosis (HR = 0.74, p < 0.001) were significantly related to time-to-death. There is a higher rate of SNAC-related death in counties with more rural populations (p = 0.027). Conclusion: Future interventions targeting rural and less well-educated populations may improve care with the goal of increasing the span of healthy life and reducing survival disparities related to SNAC.
Original language | English (US) |
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Pages (from-to) | 2946-2953 |
Number of pages | 8 |
Journal | Head and Neck |
Volume | 43 |
Issue number | 10 |
DOIs | |
State | Published - Oct 2021 |
Keywords
- SEER
- anterior skull base
- disparities
- endoscopic skull base surgery
- health disparities
- paranasal sinuses
- rhinology
- sinonasal
- sinonasal adenocarcinoma
- sinonasal malignancy
ASJC Scopus subject areas
- Otorhinolaryngology