Single center experience of capsule endoscopy in patients with obscure gastrointestinal bleeding

Mahesh Kumar Goenka, Shounak Majumder, Sanjeev Kumar, Pradeepta Kumar Sethy, Usha Goenka

Research output: Contribution to journalArticle

48 Scopus citations

Abstract

AIM: To identify optimum timing to maximize diagnostic yield by capsule endoscopy (CE) in patients with obscure gastrointestinal bleeding (OGIB). METHODS: We identified patients who underwent CE at our institution from August 2003 to December 2009. Patient medical records were reviewed to determine type of OGIB (occult, overt), CE results and complications, and timing of CE with respect to onset of bleeding. RESULTS: Out of 385 patients investigated for OGIB, 284 (74%) had some lesion detected by CE. In 222 patients (58%), definite lesions were detected that could unequivocally explain OGIB. Small bowel ulcer/erosions secondary to Crohn's disease, tuberculosis or non-steroidal anti-inflammatory agent use were the commonest lesions detected. Patients with overt GI bleeding for < 48 h before CE had the highest diagnostic yield (87%). This was significantly greater (P < 0.05) compared to that in patients with overt bleeding prior to 48 h (68%), as well as those with occult OGIB (59%). CONCLUSION: We established the importance of early CE in management of OGIB. CE within 48 h of overt bleeding has the greatest potential for lesion detection.

Original languageEnglish (US)
Pages (from-to)774-778
Number of pages5
JournalWorld journal of gastroenterology
Volume17
Issue number6
DOIs
StatePublished - Feb 14 2011

Keywords

  • Capsule endoscopy
  • Gastrointestinal bleeding

ASJC Scopus subject areas

  • Gastroenterology

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