Simultaneous bilateral thalamic hemorrhages following the administration of intravenous tissue plasminogen activator

Alexander W. Dromerick, James F Meschia, Ashok Kumar, Robert E. Hanlon

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

A patient suffered the onset of simultaneous bilateral thalamic hemorrhage several hours after the administration of intravenous tissue plasminogen activator. The patient exhibited features of the paramedian diencephalic syndrome, including executive dysfunction, anterograde amnesia, inattention, and disturbances of visual perception. During rehabilitation, she made significant gains in overlearned activities of daily living tasks, but her inability to retain new information left her severely disabled. The use of intravenous thrombolytic therapy is believed to account for this patient's unusual stroke syndrome. With recent evidence supporting the efficacy of intravenous thrombolysis in acute stroke, patients with multiple hemorrhagic strokes as a result of thrombolysis may become more common on rehabilitation services.

Original languageEnglish (US)
Pages (from-to)92-94
Number of pages3
JournalArchives of Physical Medicine and Rehabilitation
Volume78
Issue number1
DOIs
StatePublished - Jan 1997
Externally publishedYes

Fingerprint

Tissue Plasminogen Activator
Intravenous Administration
Hemorrhage
Stroke
Rehabilitation
Anterograde Amnesia
Visual Perception
Thrombolytic Therapy
Activities of Daily Living

ASJC Scopus subject areas

  • Rehabilitation

Cite this

Simultaneous bilateral thalamic hemorrhages following the administration of intravenous tissue plasminogen activator. / Dromerick, Alexander W.; Meschia, James F; Kumar, Ashok; Hanlon, Robert E.

In: Archives of Physical Medicine and Rehabilitation, Vol. 78, No. 1, 01.1997, p. 92-94.

Research output: Contribution to journalArticle

@article{17ab48e23d044c90886449efab6baeab,
title = "Simultaneous bilateral thalamic hemorrhages following the administration of intravenous tissue plasminogen activator",
abstract = "A patient suffered the onset of simultaneous bilateral thalamic hemorrhage several hours after the administration of intravenous tissue plasminogen activator. The patient exhibited features of the paramedian diencephalic syndrome, including executive dysfunction, anterograde amnesia, inattention, and disturbances of visual perception. During rehabilitation, she made significant gains in overlearned activities of daily living tasks, but her inability to retain new information left her severely disabled. The use of intravenous thrombolytic therapy is believed to account for this patient's unusual stroke syndrome. With recent evidence supporting the efficacy of intravenous thrombolysis in acute stroke, patients with multiple hemorrhagic strokes as a result of thrombolysis may become more common on rehabilitation services.",
author = "Dromerick, {Alexander W.} and Meschia, {James F} and Ashok Kumar and Hanlon, {Robert E.}",
year = "1997",
month = "1",
doi = "10.1016/S0003-9993(97)90018-6",
language = "English (US)",
volume = "78",
pages = "92--94",
journal = "Archives of Physical Medicine and Rehabilitation",
issn = "0003-9993",
publisher = "W.B. Saunders Ltd",
number = "1",

}

TY - JOUR

T1 - Simultaneous bilateral thalamic hemorrhages following the administration of intravenous tissue plasminogen activator

AU - Dromerick, Alexander W.

AU - Meschia, James F

AU - Kumar, Ashok

AU - Hanlon, Robert E.

PY - 1997/1

Y1 - 1997/1

N2 - A patient suffered the onset of simultaneous bilateral thalamic hemorrhage several hours after the administration of intravenous tissue plasminogen activator. The patient exhibited features of the paramedian diencephalic syndrome, including executive dysfunction, anterograde amnesia, inattention, and disturbances of visual perception. During rehabilitation, she made significant gains in overlearned activities of daily living tasks, but her inability to retain new information left her severely disabled. The use of intravenous thrombolytic therapy is believed to account for this patient's unusual stroke syndrome. With recent evidence supporting the efficacy of intravenous thrombolysis in acute stroke, patients with multiple hemorrhagic strokes as a result of thrombolysis may become more common on rehabilitation services.

AB - A patient suffered the onset of simultaneous bilateral thalamic hemorrhage several hours after the administration of intravenous tissue plasminogen activator. The patient exhibited features of the paramedian diencephalic syndrome, including executive dysfunction, anterograde amnesia, inattention, and disturbances of visual perception. During rehabilitation, she made significant gains in overlearned activities of daily living tasks, but her inability to retain new information left her severely disabled. The use of intravenous thrombolytic therapy is believed to account for this patient's unusual stroke syndrome. With recent evidence supporting the efficacy of intravenous thrombolysis in acute stroke, patients with multiple hemorrhagic strokes as a result of thrombolysis may become more common on rehabilitation services.

UR - http://www.scopus.com/inward/record.url?scp=0031012879&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0031012879&partnerID=8YFLogxK

U2 - 10.1016/S0003-9993(97)90018-6

DO - 10.1016/S0003-9993(97)90018-6

M3 - Article

C2 - 9014966

AN - SCOPUS:0031012879

VL - 78

SP - 92

EP - 94

JO - Archives of Physical Medicine and Rehabilitation

JF - Archives of Physical Medicine and Rehabilitation

SN - 0003-9993

IS - 1

ER -