Simulating Transplant Small-for-size Grafts Using Human Liver Monosegments: The Impact of Portal Perfusion Pressure

M. Mohamed; L. Kang; C. Zhang; B. Edenfield; J. Sykes; T. Brown; J. L. Johnson; F. Rehman; J. H. Nguyen

doi:10.1016/j.transproceed.2018.12.028

Simulating Transplant Small-for-size Grafts Using Human Liver Monosegments: The Impact of Portal Perfusion Pressure

M. Mohamed, L. Kang, C. Zhang, B. Edenfield, J. Sykes, T. Brown, J. L. Johnson, F. Rehman, J. H. Nguyen

Transplant Surgery

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Small-for-size-liver grafts (SFSG) in adult transplant recipients have elevated risk of graft failure, limiting its application in clinical liver transplantation. Relevant preclinical model of SFSG is lacking. Relevant to deceased-donor split liver transplant and living-donor liver transplant in adult recipients, in this study, we present our initial characterization of SFSG model using monosegments of a discarded human donor liver.

Original language	English (US)
Pages (from-to)	919-924
Number of pages	6
Journal	Transplantation proceedings
Volume	51
Issue number	3
DOIs	https://doi.org/10.1016/j.transproceed.2018.12.028
State	Published - Apr 2019

ASJC Scopus subject areas

Surgery
Transplantation

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10.1016/j.transproceed.2018.12.028

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abstract = "Small-for-size-liver grafts (SFSG) in adult transplant recipients have elevated risk of graft failure, limiting its application in clinical liver transplantation. Relevant preclinical model of SFSG is lacking. Relevant to deceased-donor split liver transplant and living-donor liver transplant in adult recipients, in this study, we present our initial characterization of SFSG model using monosegments of a discarded human donor liver.",

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AU - Kang, L.

AU - Zhang, C.

AU - Edenfield, B.

AU - Sykes, J.

AU - Brown, T.

AU - Johnson, J. L.

AU - Rehman, F.

AU - Nguyen, J. H.

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AB - Small-for-size-liver grafts (SFSG) in adult transplant recipients have elevated risk of graft failure, limiting its application in clinical liver transplantation. Relevant preclinical model of SFSG is lacking. Relevant to deceased-donor split liver transplant and living-donor liver transplant in adult recipients, in this study, we present our initial characterization of SFSG model using monosegments of a discarded human donor liver.

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Simulating Transplant Small-for-size Grafts Using Human Liver Monosegments: The Impact of Portal Perfusion Pressure

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ASJC Scopus subject areas

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