Simulated imaging of atherosclerotic & radiofrequency ablation lesions using phase subtraction

John R. Jameson, David R. Holmes III, Benjamin R. Buhrow, Erik S. Daniel, Barry Kent Gilbert, Clifton R Haider

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Cardiovascular diseases are the main cause of death worldwide. Atherosclerosis and atrial fibrillation are structural and electrical pathophysiology, respectively, that can lead to acute events such as stroke or myocardial infarction. We used particle-based Monte Carlo methods to simulate X-ray phase imaging of atherosclerotic plaque types IV-VIII in the aorta, iliac, and coronary arteries. We also assessed scar lesion development in radiofrequency catheter ablation treatment of atrial fibrillation by simulating lesions 2, 5, 10, 30, and 60 days post-procedure. For both applications, we found high signal-to-noise and contrast-to-noise ratios in all lesions. These results suggest that X-ray phase imaging is a viable technique for non-invasive quantitative cardiovascular lesion characterization.

Original languageEnglish (US)
Title of host publicationProceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages5630-5633
Number of pages4
Volume2015-November
ISBN (Print)9781424492718
DOIs
StatePublished - Nov 4 2015
Event37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015 - Milan, Italy
Duration: Aug 25 2015Aug 29 2015

Other

Other37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015
CountryItaly
CityMilan
Period8/25/158/29/15

Fingerprint

Ablation
Atrial Fibrillation
Noise
X-Rays
Imaging techniques
Monte Carlo Method
X rays
Catheter Ablation
Catheters
Iliac Artery
Atherosclerotic Plaques
Cicatrix
Aorta
Cause of Death
Atherosclerosis
Coronary Vessels
Monte Carlo methods
Cardiovascular Diseases
Stroke
Myocardial Infarction

ASJC Scopus subject areas

  • Computer Vision and Pattern Recognition
  • Signal Processing
  • Biomedical Engineering
  • Health Informatics

Cite this

Jameson, J. R., Holmes III, D. R., Buhrow, B. R., Daniel, E. S., Gilbert, B. K., & Haider, C. R. (2015). Simulated imaging of atherosclerotic & radiofrequency ablation lesions using phase subtraction. In Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS (Vol. 2015-November, pp. 5630-5633). [7319669] Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/EMBC.2015.7319669

Simulated imaging of atherosclerotic & radiofrequency ablation lesions using phase subtraction. / Jameson, John R.; Holmes III, David R.; Buhrow, Benjamin R.; Daniel, Erik S.; Gilbert, Barry Kent; Haider, Clifton R.

Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS. Vol. 2015-November Institute of Electrical and Electronics Engineers Inc., 2015. p. 5630-5633 7319669.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Jameson, JR, Holmes III, DR, Buhrow, BR, Daniel, ES, Gilbert, BK & Haider, CR 2015, Simulated imaging of atherosclerotic & radiofrequency ablation lesions using phase subtraction. in Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS. vol. 2015-November, 7319669, Institute of Electrical and Electronics Engineers Inc., pp. 5630-5633, 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015, Milan, Italy, 8/25/15. https://doi.org/10.1109/EMBC.2015.7319669
Jameson JR, Holmes III DR, Buhrow BR, Daniel ES, Gilbert BK, Haider CR. Simulated imaging of atherosclerotic & radiofrequency ablation lesions using phase subtraction. In Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS. Vol. 2015-November. Institute of Electrical and Electronics Engineers Inc. 2015. p. 5630-5633. 7319669 https://doi.org/10.1109/EMBC.2015.7319669
Jameson, John R. ; Holmes III, David R. ; Buhrow, Benjamin R. ; Daniel, Erik S. ; Gilbert, Barry Kent ; Haider, Clifton R. / Simulated imaging of atherosclerotic & radiofrequency ablation lesions using phase subtraction. Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS. Vol. 2015-November Institute of Electrical and Electronics Engineers Inc., 2015. pp. 5630-5633
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