Abstract
AIM: To investigate the reliability of massive hepatectomy models by using clip techniques. METHODS: We analyzed anatomical findings in 100 mice following massive hepatectomy induced by liver reduction > 70%. The impact of various factors in the different models was also analyzed, including learning curves, operative time, survival curves, and histopathological findings. RESULTS: According to anatomical results, models with 75%, 80%, and 90% hepatectomy produced massive hepatectomy. Learning curves and operative times were most optimal with the clip technique. Each hepatectomy performed using the clip technique produced a reasonable survival curve, and there were no differences in histopathological findings between the suture and clip techniques. CONCLUSION: Massive hepatectomy by the clip technique is simple and can provide reliable and relevant data.
Original language | English (US) |
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Pages (from-to) | 2767-2774 |
Number of pages | 8 |
Journal | World journal of gastroenterology |
Volume | 18 |
Issue number | 22 |
DOIs | |
State | Published - 2012 |
Keywords
- Animal model
- Clip
- Hepatectomy
- Microsurgery
- Surgical technique
ASJC Scopus subject areas
- Gastroenterology