Sildenafil for psychotropic-induced sexual dysfunction in 31 women and 61 men

Alen J. Salerian, W. Eric Deibler, Bernard J. Vittone, Susan Popowitz Geyer, Laurence Drell, Nooreddin Mirmirani, John A. Mirczak, Walter Byrd, Steven B. Tunick, Marla Wax, Staci Fleisher

Research output: Contribution to journalArticlepeer-review

28 Scopus citations


Ninety-two outpatients (31 women, 61 men) who were treated with oral sildenafil forpsychotropic-induced sexual dysfunction (PISD) completed ratings of their sexual functioning pre- and posttreat-ment. Both women and men reported significant improvements (p =.001) in all domains of sexual functioning, with 88% reporting improvement in overall sexual satisfaction. Significant improvements were reported regardless of psychotropic medication type. However, patients taking selective serotonin re-uptake inhibitors reported less improvement in arousal, libido, and overall sexual satisfaction than did other patients, whereas patients taking benzodiazepines reported significantly more improvement in libido and overall sexual satisfaction. Oral sildenafil may be an effective treatment for PISD.

Original languageEnglish (US)
Pages (from-to)133-140
Number of pages8
JournalJournal of Sex and Marital Therapy
Issue number2
StatePublished - Apr 2000

ASJC Scopus subject areas

  • Clinical Psychology


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