Significance of T-wave pseudonormalization during exercise. A radionuclide angiographic study

C. J. Lavie, Jae Kuen Oh, H. T. Mankin, I. P. Clements, E. R. Giuliani, Raymond J Gibbons

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

In 84 consecutive patients with resting T-wave inversion, radionuclide angiography revealed significant new wall motion abnormalities in 13 (28 percent) of the 47 patients with persistent T-wave inversion and in 23 (62 percent) of the 37 patients with T-wave pseudonormalization during exercise (p < 0.01). The response of the ejection fraction to exercise was better in patients with persistent T-wave inversion than in those with pseudonormalization (p < 0.04). Mechanical evidence of ischemia was seen in 14 (61 percent) of the 23 patients with T-wave pseudonormalization but without ST-segment depression. In patients with resting T-wave inversion, pseudonormalization was slightly more sensitive but less specific than a positive exercise test for predicting significant new all motion abnormalities or decreases in the ejection fraction with exercise. Although pseudonormalization is not extremely useful alone, the presence or absence of this finding can increase the diagnostic accuracy of exercise electrocardiography in patients with resting T-wave inversion and suspected ischemic heart disease.

Original languageEnglish (US)
Pages (from-to)512-516
Number of pages5
JournalChest
Volume94
Issue number3
StatePublished - 1988

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Radioisotopes
Exercise
Radionuclide Angiography
Exercise Test
Myocardial Ischemia
Electrocardiography
Ischemia

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

Cite this

Lavie, C. J., Oh, J. K., Mankin, H. T., Clements, I. P., Giuliani, E. R., & Gibbons, R. J. (1988). Significance of T-wave pseudonormalization during exercise. A radionuclide angiographic study. Chest, 94(3), 512-516.

Significance of T-wave pseudonormalization during exercise. A radionuclide angiographic study. / Lavie, C. J.; Oh, Jae Kuen; Mankin, H. T.; Clements, I. P.; Giuliani, E. R.; Gibbons, Raymond J.

In: Chest, Vol. 94, No. 3, 1988, p. 512-516.

Research output: Contribution to journalArticle

Lavie, CJ, Oh, JK, Mankin, HT, Clements, IP, Giuliani, ER & Gibbons, RJ 1988, 'Significance of T-wave pseudonormalization during exercise. A radionuclide angiographic study', Chest, vol. 94, no. 3, pp. 512-516.
Lavie, C. J. ; Oh, Jae Kuen ; Mankin, H. T. ; Clements, I. P. ; Giuliani, E. R. ; Gibbons, Raymond J. / Significance of T-wave pseudonormalization during exercise. A radionuclide angiographic study. In: Chest. 1988 ; Vol. 94, No. 3. pp. 512-516.
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AU - Oh, Jae Kuen

AU - Mankin, H. T.

AU - Clements, I. P.

AU - Giuliani, E. R.

AU - Gibbons, Raymond J

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N2 - In 84 consecutive patients with resting T-wave inversion, radionuclide angiography revealed significant new wall motion abnormalities in 13 (28 percent) of the 47 patients with persistent T-wave inversion and in 23 (62 percent) of the 37 patients with T-wave pseudonormalization during exercise (p < 0.01). The response of the ejection fraction to exercise was better in patients with persistent T-wave inversion than in those with pseudonormalization (p < 0.04). Mechanical evidence of ischemia was seen in 14 (61 percent) of the 23 patients with T-wave pseudonormalization but without ST-segment depression. In patients with resting T-wave inversion, pseudonormalization was slightly more sensitive but less specific than a positive exercise test for predicting significant new all motion abnormalities or decreases in the ejection fraction with exercise. Although pseudonormalization is not extremely useful alone, the presence or absence of this finding can increase the diagnostic accuracy of exercise electrocardiography in patients with resting T-wave inversion and suspected ischemic heart disease.

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