Significance of simple partial seizures in temporal lobe epilepsy

Joseph I. Sirven, Michael R. Sperling, Jacqueline A. French, Michael J. O'Connor

Research output: Contribution to journalArticlepeer-review

25 Scopus citations

Abstract

We determined how localization of simple partial seizures (SPS) correlated with localization of complex partial seizure (CPS) in scalp/sphenoidal EEG and assessed prognosis after temporal lobe resective surgery in patients with an ictal correlate of SPS in scalp/sphenoidal EEG recordings. EEGs were recorded with the 10-20 system of electrode placement and supplemented with sphenoidal electrodes. Between 1985 and 1992, 183 patients with temporal lobe epilepsy (TLE) reported an aura (SPS) during inpatient monitoring; all were eligible for inclusion in our study. The EEGs during SPS showed ictal changes in 51 patients (28%, 117 SPS). Forty-four patients had unilateral temporal interictal spikes (IIS), and SPS and CPS always arose from the same region. Seven patients had bitemporal interictal spikes; SPS colocalized with CPS in 4 patients (57%), SPS were contralateral to CPS in 2 patients, and 1 patient had bilateral independent CPS but unilateral SPS. SPS accompanied by EEG ictal changes conveyed a favorable prognosis in patients who underwent epilepsy surgery. Scalp/sphenoidal recorded IIS but were less reliable in identifying the location of CPS onset in patients with bitemporal spikes.

Original languageEnglish (US)
Pages (from-to)450-454
Number of pages5
JournalEpilepsia
Volume37
Issue number5
DOIs
StatePublished - May 1 1996

Keywords

  • Electroencephalography
  • Epilepsy seizures
  • Surgery
  • Temporal lobe

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

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