Abstract
This article reviews the current evidence and knowledge of progressive liver fibrosis after pediatric liver transplantation. This often-silent histologic finding is common in long-term survivors and may lead to allograft dysfunction in advanced stages. Surveillance through protocolized liver allograft biopsy remains the gold standard for diagnosis, and recent evidence suggests that chronic inflammation precedes fibrosis.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1987-1992 |
| Number of pages | 6 |
| Journal | World journal of gastroenterology |
| Volume | 26 |
| Issue number | 17 |
| DOIs | |
| State | Published - May 7 2020 |
Keywords
- Allograft fibrosis
- Chronic rejection
- Immunosuppression
- Liver allograft
- Pediatric liver transplant
- Portal inflammation
ASJC Scopus subject areas
- Gastroenterology