Signal transduction through the T-cell antigen receptor

Robert T. Abraham; Larry M. Karnitz; J. Paul Secrist; Paul J. Leibson

doi:10.1016/0968-0004(92)90015-2

Signal transduction through the T-cell antigen receptor

Robert T. Abraham, Larry M. Karnitz, J. Paul Secrist, Paul J. Leibson

Oncology

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32 Scopus citations

Abstract

The mechanism by which ligand binding to the T-cell antigen receptor triggers the T-cell activation program has long been one of the most fascinating questions in lymphocyte biology. Here, we review recent insights into the transmembrane signaling functions of this multisubunit receptor complex.

Original language	English (US)
Pages (from-to)	434-438
Number of pages	5
Journal	Trends in biochemical sciences
Volume	17
Issue number	10
DOIs	https://doi.org/10.1016/0968-0004(92)90015-2
State	Published - Oct 1992

ASJC Scopus subject areas

Biochemistry
Molecular Biology

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10.1016/0968-0004(92)90015-2

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title = "Signal transduction through the T-cell antigen receptor",

abstract = "The mechanism by which ligand binding to the T-cell antigen receptor triggers the T-cell activation program has long been one of the most fascinating questions in lymphocyte biology. Here, we review recent insights into the transmembrane signaling functions of this multisubunit receptor complex.",

author = "Abraham, {Robert T.} and Karnitz, {Larry M.} and Secrist, {J. Paul} and Leibson, {Paul J.}",

year = "1992",

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AU - Karnitz, Larry M.

AU - Secrist, J. Paul

AU - Leibson, Paul J.

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N2 - The mechanism by which ligand binding to the T-cell antigen receptor triggers the T-cell activation program has long been one of the most fascinating questions in lymphocyte biology. Here, we review recent insights into the transmembrane signaling functions of this multisubunit receptor complex.

AB - The mechanism by which ligand binding to the T-cell antigen receptor triggers the T-cell activation program has long been one of the most fascinating questions in lymphocyte biology. Here, we review recent insights into the transmembrane signaling functions of this multisubunit receptor complex.

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Signal transduction through the T-cell antigen receptor

Abstract

ASJC Scopus subject areas

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