Should We Always Defer Treatment of Kidney Disease When There Is Extensive Interstitial Fibrosis on Biopsy?

Musab S. Hommos, Andrew D. Rule

Research output: Contribution to journalReview articlepeer-review

Abstract

Severity of interstitial fibrosis and tubular atrophy (IFTA) seen on kidney biopsy has been used by nephrologist as prognostic marker of kidney disease. While IFTA is a very strong predictor of kidney failure, some patients with severe fibrosis will still not progress to kidney failure within 5 years. Treatment of underlying kidney disease in select patients with severe IFTA should be considered when risks of treatment are reasonable despite the low potential for benefit.

Original languageEnglish (US)
Pages (from-to)286-288
Number of pages3
JournalAmerican journal of nephrology
Volume44
Issue number4
DOIs
StatePublished - Oct 1 2016

Keywords

  • Interstitial fibrosis
  • Kidney
  • Outcomes
  • Prognosis
  • Renal biopsy
  • Tubular atrophy

ASJC Scopus subject areas

  • Nephrology

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