Shear Wave Elastography Quantifies Stiffness in Ex Vivo Porcine Artery with Stiffened Arterial Region

Erik Widman, Elira Maksuti, Carolina Amador, Matthew W Urban, Kenneth Caidahl, Matilda Larsson

Research output: Contribution to journalArticle

24 Scopus citations


Five small porcine aortas were used as a human carotid artery model, and their stiffness was estimated using shear wave elastography (SWE) in the arterial wall and a stiffened artery region mimicking a stiff plaque. To optimize the SWE settings, shear wave bandwidth was measured with respect to acoustic radiation force push length and number of compounded angles used for motion detection with plane wave imaging. The mean arterial wall and simulated plaque shear moduli varied from 41 ± 5 to 97 ± 10 kPa and from 86 ± 13 to 174 ± 35 kPa, respectively, over the pressure range 20–120 mmHg. The results revealed that a minimum bandwidth of approximately 1500 Hz is necessary for consistent shear modulus estimates, and a high pulse repetition frequency using no image compounding is more important than a lower pulse repetition frequency with better image quality when estimating arterial wall and plaque stiffness using SWE.

Original languageEnglish (US)
Pages (from-to)2423-2435
Number of pages13
JournalUltrasound in Medicine and Biology
Issue number10
StatePublished - 2016



  • Arteriosclerosis
  • Artery
  • Atherosclerosis
  • Elasticity
  • Ex vivo
  • Phase velocity
  • Plaque
  • Shear wave elastography
  • Ultrasound

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Biophysics
  • Radiology Nuclear Medicine and imaging

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