Abstract
This paper reports shear stiffness and viscosity "virtual biopsy" measurements of the three excised noncancerous human prostates using a new tool known as shear wave dispersion ultrasound vibrometry (SDUV) in vitro. Improved methods for prostate guided-biopsy are required to effectively guide needle biopsy to the suspected site. In addition, tissue stiffness measurement helps in identifying a suspected site to perform biopsy because stiffness has been shown to correlate with pathologies, such as cancerous tissue. More importantly, early detection of prostate cancer may guide minimally invasive therapy and eliminate insidious procedures. In this paper, "virtual biopsies" were taken in multiple locations in three excised prostates; SDUV shear elasticity and viscosity measurements were performed at the selected "suspicious" locations within the prostates. SDUV measurements of prostate elasticity and viscosity are generally in agreement with preliminary values previously reported in the literature. It is, however, important to emphasize here that the obtained viscoelastic parameters values are local, and not a mean value for the whole prostate.
Original language | English (US) |
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Article number | 5492177 |
Pages (from-to) | 235-242 |
Number of pages | 8 |
Journal | IEEE Transactions on Biomedical Engineering |
Volume | 58 |
Issue number | 2 |
DOIs | |
State | Published - Feb 2011 |
Keywords
- Prostate
- radiation force
- shear wave
- ultrasound
- viscoelastic
ASJC Scopus subject areas
- Biomedical Engineering