Shear Stiffness Estimation Using Intravoxel Phase Dispersion in Magnetic Resonance Elastography

Kevin J. Glaser, Joel P. Felmlee, Armando Manduca, Richard L. Ehman

Research output: Contribution to journalArticle

24 Scopus citations

Abstract

Dynamic MR elastography (MRE) is a phase-contrast technique in which the periodic shear motion of an object is encoded as variations in the phase of the reconstructed images. An alternative MRE method is presented whereby waves are depicted as intensity variations in the magnitude images due to intravoxel phase dispersion (IVPD). A theoretical framework is developed to model how the IVPD magnitude data are related to the underlying shear wave motion, and how they can be used to estimate shear stiffness. The results are shown in a series of phantom experiments to demonstrate that IVPD MRE complements phase-contrast MRE.

Original languageEnglish (US)
Pages (from-to)1256-1265
Number of pages10
JournalMagnetic Resonance in Medicine
Volume50
Issue number6
DOIs
StatePublished - Dec 1 2003

Keywords

  • Elasticity
  • Intravoxel phase dispersion
  • Magnetic resonance elastography
  • Shear stiffness
  • Tissue characterization

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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