TY - JOUR
T1 - Sex differences in acute cardiovascular care
T2 - A review and needs assessment
AU - Vallabhajosyula, Saraschandra
AU - Verghese, Dhiran
AU - Desai, Viral K.
AU - Sundaragiri, Pranathi R.
AU - Miller, Virginia M.
N1 - Publisher Copyright:
© 2021 The Author(s) 2021. Published by Oxford University Press on behalf of the European Society of Cardiology.
PY - 2022/2/1
Y1 - 2022/2/1
N2 - Despite significant progress in the care of patients suffering from cardiovascular disease, there remains a persistent sex disparity in the diagnosis, management, and outcomes of these patients. These sex disparities are seen across the spectrum of cardiovascular care, but, are especially pronounced in acute cardiovascular care. The spectrum of acute cardiovascular care encompasses critically ill or tenuous patients with cardiovascular conditions that require urgent or emergent decision-making and interventions. In this narrative review, the disparities in the clinical course, management, and outcomes of six commonly encountered acute cardiovascular conditions, some with a known sex-predilection will be discussed within the basis of underlying sex differences in physiology, anatomy, and pharmacology with the goal of identifying areas where improvement in clinical approaches are needed.
AB - Despite significant progress in the care of patients suffering from cardiovascular disease, there remains a persistent sex disparity in the diagnosis, management, and outcomes of these patients. These sex disparities are seen across the spectrum of cardiovascular care, but, are especially pronounced in acute cardiovascular care. The spectrum of acute cardiovascular care encompasses critically ill or tenuous patients with cardiovascular conditions that require urgent or emergent decision-making and interventions. In this narrative review, the disparities in the clinical course, management, and outcomes of six commonly encountered acute cardiovascular conditions, some with a known sex-predilection will be discussed within the basis of underlying sex differences in physiology, anatomy, and pharmacology with the goal of identifying areas where improvement in clinical approaches are needed.
KW - Acute heart failure
KW - Acute myocardial infarction
KW - Cardiac arrest
KW - Cardiogenic shock
KW - Female
KW - Sex differences
KW - Spontaneous coronary artery dissection
KW - Takotsubo cardiomyopathy
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U2 - 10.1093/cvr/cvab063
DO - 10.1093/cvr/cvab063
M3 - Review article
C2 - 33734314
AN - SCOPUS:85125002037
SN - 0008-6363
VL - 118
SP - 667
EP - 685
JO - Cardiovascular research
JF - Cardiovascular research
IS - 3
ER -