Sex differences in α-adrenergic support of blood pressure

Judith A M Schmitt, Michael Joseph Joyner, Nisha Charkoudian, B. Gunnar Wallin, Emma C. Hart

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

We tested whether the inter-individual variability in a-adrenergic support of blood pressure plays a critical role in the sex differences in tonic support of blood pressure by the autonomic nervous system. Blockade of the α-adrenergic receptors was achieved via phentolamine and showed a smaller (Pα0.05) decrease in blood pressure in women compared to men, implying that a-adrenergic support of blood pressure is less in women than in men.

Original languageEnglish (US)
Pages (from-to)271-275
Number of pages5
JournalClinical Autonomic Research
Volume20
Issue number4
DOIs
StatePublished - Aug 2010

Fingerprint

Sex Characteristics
Adrenergic Agents
Blood Pressure
Phentolamine
Autonomic Nervous System
Adrenergic Receptors

Keywords

  • α-Adrenergic
  • Blood pressure
  • Sex differences

ASJC Scopus subject areas

  • Clinical Neurology
  • Endocrine and Autonomic Systems

Cite this

Sex differences in α-adrenergic support of blood pressure. / Schmitt, Judith A M; Joyner, Michael Joseph; Charkoudian, Nisha; Wallin, B. Gunnar; Hart, Emma C.

In: Clinical Autonomic Research, Vol. 20, No. 4, 08.2010, p. 271-275.

Research output: Contribution to journalArticle

Schmitt, JAM, Joyner, MJ, Charkoudian, N, Wallin, BG & Hart, EC 2010, 'Sex differences in α-adrenergic support of blood pressure', Clinical Autonomic Research, vol. 20, no. 4, pp. 271-275. https://doi.org/10.1007/s10286-010-0061-y
Schmitt, Judith A M ; Joyner, Michael Joseph ; Charkoudian, Nisha ; Wallin, B. Gunnar ; Hart, Emma C. / Sex differences in α-adrenergic support of blood pressure. In: Clinical Autonomic Research. 2010 ; Vol. 20, No. 4. pp. 271-275.
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