Sex differences in α-adrenergic support of blood pressure

Judith A.M. Schmitt, Michael J. Joyner, Nisha Charkoudian, B. Gunnar Wallin, Emma C. Hart

Research output: Contribution to journalArticle

27 Scopus citations

Abstract

We tested whether the inter-individual variability in a-adrenergic support of blood pressure plays a critical role in the sex differences in tonic support of blood pressure by the autonomic nervous system. Blockade of the α-adrenergic receptors was achieved via phentolamine and showed a smaller (Pα0.05) decrease in blood pressure in women compared to men, implying that a-adrenergic support of blood pressure is less in women than in men.

Original languageEnglish (US)
Pages (from-to)271-275
Number of pages5
JournalClinical Autonomic Research
Volume20
Issue number4
DOIs
StatePublished - Aug 2010

Keywords

  • Blood pressure
  • Sex differences
  • α-Adrenergic

ASJC Scopus subject areas

  • Endocrine and Autonomic Systems
  • Clinical Neurology

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