Severe, Reversible Pulmonary Hypertension in a Patient with Monoclonal Gammopathy and Features of Dermatomyositis

Sheraz Yaqub, Kevin G. Moder, Martha Lacy

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Pulmonary hypertension is an extremely serious and potentially fatal disorder. Although pulmonary hypertension is a potential complication of connective tissue disease, it has been reported rarely in patients with dermatomyositis. Similarly, multiple myeloma is rare in patients with dermatomyositis. We describe a patient with severe pulmonary hypertension who also had features of dermatomyositis and monoclonal gammopathy. To our knowledge, this is the first reported case of a patient in whom all 3 disorders occurred concurrently. Even more striking is the fact that the patient responded to treatment with cyclophosphamide and prostacyclin. He is asymptomatic more than 5 years after treatment was discontinued.

Original languageEnglish (US)
Pages (from-to)687-689
Number of pages3
JournalMayo Clinic Proceedings
Volume79
Issue number5
DOIs
StatePublished - Jan 1 2004

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Paraproteinemias
Dermatomyositis
Pulmonary Hypertension
Connective Tissue Diseases
Epoprostenol
Multiple Myeloma
Cyclophosphamide
Therapeutics

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Severe, Reversible Pulmonary Hypertension in a Patient with Monoclonal Gammopathy and Features of Dermatomyositis. / Yaqub, Sheraz; Moder, Kevin G.; Lacy, Martha.

In: Mayo Clinic Proceedings, Vol. 79, No. 5, 01.01.2004, p. 687-689.

Research output: Contribution to journalArticle

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