Severe Fever with Thrombocytopenia Syndrome Associated with a Novel Bunyavirus

Keita Matsuno, Heinz Feldmann, Hideki Ebihara

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations

Abstract

Severe fever with thrombocytopenia syndrome virus (SFTSV) is a newly recognized pathogen and the first highly pathogenic tick-borne virus reported in the genus Phlebovirus, family Bunyaviridae. Except for some basic knowledge on viral biology and epidemiology as well as the establishment of diagnostics and the description of the clinical disease syndrome, little is known about this emerging pathogen. Currently, there are neither therapeutic approaches nor vaccines available for the treatment and prophylaxis of SFTSV infections. In the absence of more thorough ecology and epidemiology, prevention is based on education targeting towards avoiding exposure through ticks and blood and secretions/excretions of patients. Urgently needed are further studies on the pathogenesis and host responses to infection in order to define targets for therapeutic intervention and strategies for vaccination.

Original languageEnglish (US)
Title of host publicationEmerging Infectious Diseases
Subtitle of host publicationClinical Case Studies
PublisherElsevier Inc.
Pages1-12
Number of pages12
ISBN (Electronic)9780124201095
ISBN (Print)9780124169753
DOIs
StatePublished - May 16 2014
Externally publishedYes

Keywords

  • Diagnosis
  • Disease control
  • Epidemiology
  • Pathogenesis
  • Phlebovirus
  • Severe fever with thrombocytopenia syndrome virus
  • SFTSV
  • Tick-borne disease

ASJC Scopus subject areas

  • Medicine(all)
  • Immunology and Microbiology(all)

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  • Cite this

    Matsuno, K., Feldmann, H., & Ebihara, H. (2014). Severe Fever with Thrombocytopenia Syndrome Associated with a Novel Bunyavirus. In Emerging Infectious Diseases: Clinical Case Studies (pp. 1-12). Elsevier Inc.. https://doi.org/10.1016/B978-0-12-416975-3.00001-7