TY - JOUR
T1 - Severe cholestasis related to itraconazole for the treatment of onychomycosis
AU - Talwalkar, Jayant A.
AU - Soetikno, Roy E.
AU - Carr-Locke, David L.
AU - Berg, Carl L.
PY - 1999/12
Y1 - 1999/12
N2 - We describe a case of prolonged cholestasis temporally associated with the use of itraconazole for onychomycosis. Peak bilirubin level of 32.0 mg/dl was documented approximately 2 months after discontinuation of the patient's itraconazole therapy, with symptoms of cholestasis persisting more than 1 month after the peak in bilirubin. Physicians should be aware of the potential for severe cholestasis associated with itraconazole usage.
AB - We describe a case of prolonged cholestasis temporally associated with the use of itraconazole for onychomycosis. Peak bilirubin level of 32.0 mg/dl was documented approximately 2 months after discontinuation of the patient's itraconazole therapy, with symptoms of cholestasis persisting more than 1 month after the peak in bilirubin. Physicians should be aware of the potential for severe cholestasis associated with itraconazole usage.
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U2 - 10.1016/S0002-9270(99)00682-6
DO - 10.1016/S0002-9270(99)00682-6
M3 - Article
C2 - 10606333
AN - SCOPUS:0032779118
SN - 0002-9270
VL - 94
SP - 3632
EP - 3633
JO - American Journal of Gastroenterology
JF - American Journal of Gastroenterology
IS - 12
ER -