Severe capecitabine toxicity associated with a rare DPYD variant identified through whole-genome sequencing

Reynold C. Ly; Remington E. Schmidt; Patrick J. Kiel; Victoria M. Pratt; Bryan P. Schneider; Milan Radovich; Steven M. Offer; Robert B. Diasio; Todd C. Skaar

doi:10.1200/PO.20.00067

Severe capecitabine toxicity associated with a rare DPYD variant identified through whole-genome sequencing

Reynold C. Ly, Remington E. Schmidt, Patrick J. Kiel, Victoria M. Pratt, Bryan P. Schneider, Milan Radovich, Steven M. Offer, Robert B. Diasio, Todd C. Skaar

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Original language	English (US)
Pages (from-to)	632-638
Number of pages	7
Journal	JCO Precision Oncology
Volume	4
DOIs	https://doi.org/10.1200/PO.20.00067
State	Published - 2020

ASJC Scopus subject areas

Oncology
Cancer Research

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10.1200/PO.20.00067

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@article{00ec4a842abb491bb401651d5f0494af,

title = "Severe capecitabine toxicity associated with a rare DPYD variant identified through whole-genome sequencing",

author = "Ly, {Reynold C.} and Schmidt, {Remington E.} and Kiel, {Patrick J.} and Pratt, {Victoria M.} and Schneider, {Bryan P.} and Milan Radovich and Offer, {Steven M.} and Diasio, {Robert B.} and Skaar, {Todd C.}",

note = "Funding Information: Supported by National Institutes of Health (NIH) Grant No. R35GM131812 (T.C.S.), NIH Grant No. P30CA15083 (R.B.D.), Vera Bradley Foundation (R.C.L., M.R., B.P.S.), and the Indiana University Grand Challenge Precision Health Initiative (M.R., B.P.S., T.C.S.). We thank Surendra Buddi for bioinformatic support. Funding Information: Supported by National Institutes of Health (NIH) Grant No. R35GM131812 (T.C.S.), NIH Grant No. P30CA15083 (R.B.D.), Vera Bradley Foundation (R.C.L., M.R., B.P.S.), and the Indiana University Grand Challenge Precision Health Initiative (M.R., B.P.S., T.C.S.).",

year = "2020",

doi = "10.1200/PO.20.00067",

language = "English (US)",

volume = "4",

pages = "632--638",

journal = "JCO Precision Oncology",

issn = "2473-4284",

publisher = "American Society of Clinical Oncology",

}

TY - JOUR

T1 - Severe capecitabine toxicity associated with a rare DPYD variant identified through whole-genome sequencing

AU - Ly, Reynold C.

AU - Schmidt, Remington E.

AU - Kiel, Patrick J.

AU - Pratt, Victoria M.

AU - Schneider, Bryan P.

AU - Radovich, Milan

AU - Offer, Steven M.

AU - Diasio, Robert B.

AU - Skaar, Todd C.

N1 - Funding Information: Supported by National Institutes of Health (NIH) Grant No. R35GM131812 (T.C.S.), NIH Grant No. P30CA15083 (R.B.D.), Vera Bradley Foundation (R.C.L., M.R., B.P.S.), and the Indiana University Grand Challenge Precision Health Initiative (M.R., B.P.S., T.C.S.). We thank Surendra Buddi for bioinformatic support. Funding Information: Supported by National Institutes of Health (NIH) Grant No. R35GM131812 (T.C.S.), NIH Grant No. P30CA15083 (R.B.D.), Vera Bradley Foundation (R.C.L., M.R., B.P.S.), and the Indiana University Grand Challenge Precision Health Initiative (M.R., B.P.S., T.C.S.).

PY - 2020

Y1 - 2020

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UR - http://www.scopus.com/inward/citedby.url?scp=85090910708&partnerID=8YFLogxK

U2 - 10.1200/PO.20.00067

DO - 10.1200/PO.20.00067

M3 - Article

AN - SCOPUS:85090910708

SN - 2473-4284

VL - 4

SP - 632

EP - 638

JO - JCO Precision Oncology

JF - JCO Precision Oncology

ER -

Severe capecitabine toxicity associated with a rare DPYD variant identified through whole-genome sequencing

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