Severe Acute Cardiopulmonary Failure Related to Gadobutrol Magnetic Resonance Imaging Contrast Reaction: Successful Resuscitation with Extracorporeal Membrane Oxygenation

Pramod K. Guru, J. Kyle Bohman, Chad J. Fleming, Hon L. Tan, Devang K. Sanghavi, Alice Gallo De Moraes, Gregory W. Barsness, Erica D. Wittwer, Bernard Francis King, Grace M. Arteaga, Randall Flick, Gregory J. Schears

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

Nonanaphylactic noncardiogenic pulmonary edema leading to cardiorespiratory arrest related to the magnetic resonance imaging contrast agent gadobutrol has rarely been reported in the literature. Rarer is the association of hypokalemia with acidosis. We report 2 patients who had severe pulmonary edema associated with the use of gadobutrol contrast in the absence of other inciting agents or events. These cases were unique not only for their rare and severe presentations but also because they exemplified the increasing role of extracorporeal membrane oxygenation in resuscitation. Emergency extracorporeal membrane oxygenation resuscitation can be rapidly initiated and successful in the setting of a well-organized workflow, and it is a viable alternative and helps improve patient outcome in cases refractory to conventional resuscitative measures.

Original languageEnglish (US)
Pages (from-to)362-366
Number of pages5
JournalMayo Clinic Proceedings
Volume91
Issue number3
DOIs
StatePublished - Mar 1 2016

ASJC Scopus subject areas

  • Medicine(all)

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