TY - JOUR
T1 - Sesquiterpene lactones from Achillea crithmifolia
AU - Milosavljevic, S.
AU - Macura, S.
AU - Stefanovic, M.
AU - Aljancic, I.
AU - Milinkovk, D.
N1 - Funding Information:
Acknawiedgements--This project has been subsidized by the National Program of Pharmaceutical Research and Development (No. FAR88-00501), Gobierno de Canarias (No. 12/32.07.89)a nd AXETI.
Funding Information:
Acknowledgements-Thea uthors are very grateful to the Serbian Academyo f Sciencea nd Arts, and to the Serbian Republic ResearchF und for financial support. We wish to acknowledgoeu rg ratitudeto Professor3 .L . Markleyf or theu se of theN MR facilitya t theD epartmenot f BiochemistryU, niver-sity of Wisconsin,M adison,U .S.A.
PY - 1994
Y1 - 1994
N2 - The isolation of three highly oxygenated guaianolides, desacetyl-1α-4α- dihydroxybishopsolicepolide [1], its 4β-hydroxy epimer 2 (a new compound), and 1β,2β:3β,4β-diepoxy-8α,10α-dihydroxyguai-12(13)-en-12,6α-olide [3], from the aerial parts of Achillea crithmifolia is reported. Because lactone 3 was shown to be identical with rupin A, the initially proposed 1α,2α:3α,4α-diepoxy stereochemistry of rupin A should be revised.
AB - The isolation of three highly oxygenated guaianolides, desacetyl-1α-4α- dihydroxybishopsolicepolide [1], its 4β-hydroxy epimer 2 (a new compound), and 1β,2β:3β,4β-diepoxy-8α,10α-dihydroxyguai-12(13)-en-12,6α-olide [3], from the aerial parts of Achillea crithmifolia is reported. Because lactone 3 was shown to be identical with rupin A, the initially proposed 1α,2α:3α,4α-diepoxy stereochemistry of rupin A should be revised.
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U2 - 10.1021/np50103a008
DO - 10.1021/np50103a008
M3 - Article
AN - SCOPUS:0028280593
SN - 0163-3864
VL - 57
SP - 64
EP - 67
JO - Journal of Natural Products
JF - Journal of Natural Products
IS - 1
ER -