Serologic and genetic aspects of murine Ia antigens

The identification of the murine Ia antigens and their use as serological markers to study Ir gene products have provided plenty of productive research in this area for the past couple of years. Some observers have termed it the 'Immunodelirium'. The involvement of Ia in several important immune phenomena has prompted a search for Ia like antigens in other species including man (reviewed in this volume). Further studies on the serological and chemical nature of Ia antigens and biochemical data to show differences between molecules carrying different specificities should provide valuable insight into Ir gene product.