Abstract
Although first identified just >4 decades ago, methicillin-resistant Staphylococcus aureus (MRSA) has undergone rapid evolutionary changes and epidemiologic expansion to become a major cause of nosocomial and community-acquired infections worldwide. Increasing resistance to vancomycin among MRSA strains in conjunction with availability of new antibiotics, including daptomycin and linezolid, have increased treatment choices but made clinical treatment decisions more challenging. This article describes the clinical features and management issues of 2 challenging-to-treat manifestations of MRSA infection, bacteremia and/or endocarditis and osteomyelitis. It also presents a brief review of community-associated MRSA infections and preventive strategies directed against MRSA.
| Original language | English (US) |
|---|---|
| Journal | Clinical Infectious Diseases |
| Volume | 51 |
| Issue number | SUPPL. 2 |
| DOIs | |
| State | Published - Sep 15 2010 |
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ASJC Scopus subject areas
- Infectious Diseases
- Microbiology (medical)
Cite this
Serious infections caused by methicillin-resistant Staphylococcus aureus. / Boucher, Helen; Miller, Loren G.; Razonable, Raymund R.
In: Clinical Infectious Diseases, Vol. 51, No. SUPPL. 2, 15.09.2010.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Serious infections caused by methicillin-resistant Staphylococcus aureus
AU - Boucher, Helen
AU - Miller, Loren G.
AU - Razonable, Raymund R
PY - 2010/9/15
Y1 - 2010/9/15
N2 - Although first identified just >4 decades ago, methicillin-resistant Staphylococcus aureus (MRSA) has undergone rapid evolutionary changes and epidemiologic expansion to become a major cause of nosocomial and community-acquired infections worldwide. Increasing resistance to vancomycin among MRSA strains in conjunction with availability of new antibiotics, including daptomycin and linezolid, have increased treatment choices but made clinical treatment decisions more challenging. This article describes the clinical features and management issues of 2 challenging-to-treat manifestations of MRSA infection, bacteremia and/or endocarditis and osteomyelitis. It also presents a brief review of community-associated MRSA infections and preventive strategies directed against MRSA.
AB - Although first identified just >4 decades ago, methicillin-resistant Staphylococcus aureus (MRSA) has undergone rapid evolutionary changes and epidemiologic expansion to become a major cause of nosocomial and community-acquired infections worldwide. Increasing resistance to vancomycin among MRSA strains in conjunction with availability of new antibiotics, including daptomycin and linezolid, have increased treatment choices but made clinical treatment decisions more challenging. This article describes the clinical features and management issues of 2 challenging-to-treat manifestations of MRSA infection, bacteremia and/or endocarditis and osteomyelitis. It also presents a brief review of community-associated MRSA infections and preventive strategies directed against MRSA.
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UR - http://www.scopus.com/inward/citedby.url?scp=77957868388&partnerID=8YFLogxK
U2 - 10.1086/653519
DO - 10.1086/653519
M3 - Article
C2 - 20731576
AN - SCOPUS:77957868388
VL - 51
JO - Clinical Infectious Diseases
JF - Clinical Infectious Diseases
SN - 1058-4838
IS - SUPPL. 2
ER -