Serious bacterial infections of the skin and soft tissues

Mark D Sawyer, D. L. Dunn

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Investigation of serious bacterial soft-tissue infections has been proceeding on a broad front: from clinical studies to molecular biological analysis. Characterization of microbial toxins that account for the characteristic pathobiology of clostridial infections has been proceeding on the molecular level. Magnetic resonance imaging is emerging as an important diagnostic adjunct in severe soft-tissue infections. Studies of the relatively new glycopeptide, teicoplanin, have progressed to comparative clinical trials, and the use of hyperbaric oxygen continues to undergo scrutiny. Despite these advances in knowledge, however, the treatment for these infections remains the same: early recognition, aggressive surgical excision and debridement of affected tissues, and early, empiric broad-spectrum antimicrobial therapy.

Original languageEnglish (US)
Pages (from-to)293-297
Number of pages5
JournalCurrent Opinion in Infectious Diseases
Volume8
Issue number4
StatePublished - 1995
Externally publishedYes

Fingerprint

Soft Tissue Infections
Bacterial Infections
Teicoplanin
Skin
Glycopeptides
Debridement
Infection
Magnetic Resonance Imaging
Clinical Trials
Oxygen
Therapeutics
Clinical Studies

ASJC Scopus subject areas

  • Immunology
  • Microbiology (medical)

Cite this

Serious bacterial infections of the skin and soft tissues. / Sawyer, Mark D; Dunn, D. L.

In: Current Opinion in Infectious Diseases, Vol. 8, No. 4, 1995, p. 293-297.

Research output: Contribution to journalArticle

@article{876229d523e749abb82f7036914c1e30,
title = "Serious bacterial infections of the skin and soft tissues",
abstract = "Investigation of serious bacterial soft-tissue infections has been proceeding on a broad front: from clinical studies to molecular biological analysis. Characterization of microbial toxins that account for the characteristic pathobiology of clostridial infections has been proceeding on the molecular level. Magnetic resonance imaging is emerging as an important diagnostic adjunct in severe soft-tissue infections. Studies of the relatively new glycopeptide, teicoplanin, have progressed to comparative clinical trials, and the use of hyperbaric oxygen continues to undergo scrutiny. Despite these advances in knowledge, however, the treatment for these infections remains the same: early recognition, aggressive surgical excision and debridement of affected tissues, and early, empiric broad-spectrum antimicrobial therapy.",
author = "Sawyer, {Mark D} and Dunn, {D. L.}",
year = "1995",
language = "English (US)",
volume = "8",
pages = "293--297",
journal = "Current Opinion in Infectious Diseases",
issn = "0951-7375",
publisher = "Lippincott Williams and Wilkins",
number = "4",

}

TY - JOUR

T1 - Serious bacterial infections of the skin and soft tissues

AU - Sawyer, Mark D

AU - Dunn, D. L.

PY - 1995

Y1 - 1995

N2 - Investigation of serious bacterial soft-tissue infections has been proceeding on a broad front: from clinical studies to molecular biological analysis. Characterization of microbial toxins that account for the characteristic pathobiology of clostridial infections has been proceeding on the molecular level. Magnetic resonance imaging is emerging as an important diagnostic adjunct in severe soft-tissue infections. Studies of the relatively new glycopeptide, teicoplanin, have progressed to comparative clinical trials, and the use of hyperbaric oxygen continues to undergo scrutiny. Despite these advances in knowledge, however, the treatment for these infections remains the same: early recognition, aggressive surgical excision and debridement of affected tissues, and early, empiric broad-spectrum antimicrobial therapy.

AB - Investigation of serious bacterial soft-tissue infections has been proceeding on a broad front: from clinical studies to molecular biological analysis. Characterization of microbial toxins that account for the characteristic pathobiology of clostridial infections has been proceeding on the molecular level. Magnetic resonance imaging is emerging as an important diagnostic adjunct in severe soft-tissue infections. Studies of the relatively new glycopeptide, teicoplanin, have progressed to comparative clinical trials, and the use of hyperbaric oxygen continues to undergo scrutiny. Despite these advances in knowledge, however, the treatment for these infections remains the same: early recognition, aggressive surgical excision and debridement of affected tissues, and early, empiric broad-spectrum antimicrobial therapy.

UR - http://www.scopus.com/inward/record.url?scp=0029116361&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0029116361&partnerID=8YFLogxK

M3 - Article

VL - 8

SP - 293

EP - 297

JO - Current Opinion in Infectious Diseases

JF - Current Opinion in Infectious Diseases

SN - 0951-7375

IS - 4

ER -