Serial Doppler echocardiographic assessment of left and right ventricular performance after a first myocardial infarction

Jacob E. Moller, Eva Sondergaard, Steen H. Poulsen, Christopher P. Appleton, Kenneth Egstrup

Research output: Contribution to journalArticle

66 Scopus citations


We sought to investigate the relation between left ventricular (LV) and right ventricular (RV) function assessed with the Doppler-derived myocardial performance index (MPI), to assess serial changes, and to investigate the prognostic value of biventricular assessment of cardiac function after a first myocardial infarction (MI). To do so, serial Doppler echocardiography was performed in 77 consecutive patients with a first MI. Right ventricular MPI correlated significantly with LV MPI (r = 0.51, P < .0001). In patients with echocardiographic signs of RV MI, the RV MPI was significantly higher (0.59 ± 0.18 versus 0.44 ± 0.19, P = .001), whereas no difference in LV MPI was seen (0.55 ± 0.19 versus 0.56 ± 0.13, P = not significant). Right ventricular MPI showed a rapid normalization during follow-up, whereas LV MPI did not decrease. During follow-up, 23 patients died of cardiac causes or were readmitted because of worsening heart failure. Multivariate Cox analysis indicated LV MPI (relative risk 4.9 [95% CI 1.8-13.5], P = .002) and RV MPI (relative risk 3.8 [1.3-17.0], P = .01) to be predictors of cardiac events. Thus the RV MPI is frequently abnormal after a first MI but normalizes rapidly on follow-up, and biventricular assessment of cardiac function may improve the prognostic accuracy compared with LV assessment alone.

Original languageEnglish (US)
Pages (from-to)249-255
Number of pages7
JournalJournal of the American Society of Echocardiography
Issue number4
StatePublished - Jan 1 2001


ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

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