TY - JOUR
T1 - Serial Doppler echocardiographic assessment of left and right ventricular performance after a first myocardial infarction
AU - Moller, Jacob E.
AU - Sondergaard, Eva
AU - Poulsen, Steen H.
AU - Appleton, Christopher P.
AU - Egstrup, Kenneth
N1 - Funding Information:
The study was supported by a grant from the Danish Heart Foundation.
Copyright:
Copyright 2017 Elsevier B.V., All rights reserved.
PY - 2001
Y1 - 2001
N2 - We sought to investigate the relation between left ventricular (LV) and right ventricular (RV) function assessed with the Doppler-derived myocardial performance index (MPI), to assess serial changes, and to investigate the prognostic value of biventricular assessment of cardiac function after a first myocardial infarction (MI). To do so, serial Doppler echocardiography was performed in 77 consecutive patients with a first MI. Right ventricular MPI correlated significantly with LV MPI (r = 0.51, P < .0001). In patients with echocardiographic signs of RV MI, the RV MPI was significantly higher (0.59 ± 0.18 versus 0.44 ± 0.19, P = .001), whereas no difference in LV MPI was seen (0.55 ± 0.19 versus 0.56 ± 0.13, P = not significant). Right ventricular MPI showed a rapid normalization during follow-up, whereas LV MPI did not decrease. During follow-up, 23 patients died of cardiac causes or were readmitted because of worsening heart failure. Multivariate Cox analysis indicated LV MPI (relative risk 4.9 [95% CI 1.8-13.5], P = .002) and RV MPI (relative risk 3.8 [1.3-17.0], P = .01) to be predictors of cardiac events. Thus the RV MPI is frequently abnormal after a first MI but normalizes rapidly on follow-up, and biventricular assessment of cardiac function may improve the prognostic accuracy compared with LV assessment alone.
AB - We sought to investigate the relation between left ventricular (LV) and right ventricular (RV) function assessed with the Doppler-derived myocardial performance index (MPI), to assess serial changes, and to investigate the prognostic value of biventricular assessment of cardiac function after a first myocardial infarction (MI). To do so, serial Doppler echocardiography was performed in 77 consecutive patients with a first MI. Right ventricular MPI correlated significantly with LV MPI (r = 0.51, P < .0001). In patients with echocardiographic signs of RV MI, the RV MPI was significantly higher (0.59 ± 0.18 versus 0.44 ± 0.19, P = .001), whereas no difference in LV MPI was seen (0.55 ± 0.19 versus 0.56 ± 0.13, P = not significant). Right ventricular MPI showed a rapid normalization during follow-up, whereas LV MPI did not decrease. During follow-up, 23 patients died of cardiac causes or were readmitted because of worsening heart failure. Multivariate Cox analysis indicated LV MPI (relative risk 4.9 [95% CI 1.8-13.5], P = .002) and RV MPI (relative risk 3.8 [1.3-17.0], P = .01) to be predictors of cardiac events. Thus the RV MPI is frequently abnormal after a first MI but normalizes rapidly on follow-up, and biventricular assessment of cardiac function may improve the prognostic accuracy compared with LV assessment alone.
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U2 - 10.1067/mje.2001.111478
DO - 10.1067/mje.2001.111478
M3 - Article
C2 - 11287887
AN - SCOPUS:0008626238
SN - 0894-7317
VL - 14
SP - 249
EP - 255
JO - Journal of the American Society of Echocardiography
JF - Journal of the American Society of Echocardiography
IS - 4
ER -