TY - JOUR
T1 - Sequential multifocal electroretinogram findings in a case of Purtscher-like retinopathy
AU - Haq, Faisal
AU - Vajaranant, Thasarat S.
AU - Szlyk, Janet P.
AU - Pulido, Jose S.
N1 - Funding Information:
This work was supported by grants from the Rehabilitation Research and Development Service of the US Department of Veterans Affairs, Washington, DC (J.P.S.), center grant from The Foundation Fighting Blindness, Hunt Valley, Maryland (University of Illinois at Chicago), an unrestricted departmental grant from Research to Prevent Blindness, Inc. (University of Illinois at Chicago), and NIH core grant EY 01792 (University of Illinois at Chicago).
PY - 2002
Y1 - 2002
N2 - PURPOSE: To report the multifocal electroretinographic findings of a patient with pancreatitis-associated Purtscher-like retinopathy. DESIGN: Observational case report. METHODS: A 20-year-old man with a history of alcohol abuse and acute pancreatitis underwent multifocal electroretinography (mfERG; 103-scaled hexagons, 8-minute recording time) at 1 week, 4 weeks, and 6 months after the onset of the retinopathy. RESULTS: At 1 week, the patient had extensive cotton- wool spots in the posterior pole bilaterally, and visual acuity was significantly reduced. Both the A-waves and B-waves of the mfERG were depressed in the corresponding areas. At 4 weeks, neither visual acuity nor mfERG showed improvement, although the cotton-wool spots had resolved. Interestingly, at 6 months, visual acuity had improved significantly in the left eye, consistent with increased ratios of mfERG responses for the central area. CONCLUSION: There was no selective reduction of b-waves of the mfERG as anticipated in isolated inner retinal pathology. In this case, both the A-waves and B-waves were reduced, suggesting damage to both outer and inner retinal layers.
AB - PURPOSE: To report the multifocal electroretinographic findings of a patient with pancreatitis-associated Purtscher-like retinopathy. DESIGN: Observational case report. METHODS: A 20-year-old man with a history of alcohol abuse and acute pancreatitis underwent multifocal electroretinography (mfERG; 103-scaled hexagons, 8-minute recording time) at 1 week, 4 weeks, and 6 months after the onset of the retinopathy. RESULTS: At 1 week, the patient had extensive cotton- wool spots in the posterior pole bilaterally, and visual acuity was significantly reduced. Both the A-waves and B-waves of the mfERG were depressed in the corresponding areas. At 4 weeks, neither visual acuity nor mfERG showed improvement, although the cotton-wool spots had resolved. Interestingly, at 6 months, visual acuity had improved significantly in the left eye, consistent with increased ratios of mfERG responses for the central area. CONCLUSION: There was no selective reduction of b-waves of the mfERG as anticipated in isolated inner retinal pathology. In this case, both the A-waves and B-waves were reduced, suggesting damage to both outer and inner retinal layers.
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U2 - 10.1016/S0002-9394(02)01474-5
DO - 10.1016/S0002-9394(02)01474-5
M3 - Article
C2 - 12095823
AN - SCOPUS:0036297277
VL - 134
SP - 125
EP - 128
JO - American Journal of Ophthalmology
JF - American Journal of Ophthalmology
SN - 0002-9394
IS - 1
ER -