Septo-optic dysplasia: The clinical insignificance of an absent septum pellucidum

J. Williams, Michael C Brodsky, M. Griebel, C. M. Glasier, D. Caldwell, P. Thomas

Research output: Contribution to journalArticle

44 Citations (Scopus)

Abstract

Neurodevelopmental assessments were performed on seven patients with optic nerve hypoplasia and absence of the septum pellucidum on MRI. The evaluation included neurological status, language development, neuropsychological functioning, and behavioral and emotional adjustment. Six of the seven were found to have normal cognitive development, intact neurological status, normal language development and age-appropriate behavior. Abnormal findings included early poor motor coordination, which was felt to be closely related to decreased visual acuity, as well as subtle visual attentional problems which occurred even in patients who had normal vision in one eye. Congenital absence of the septum pellucidum was not associated with significant intellectual, behavioral or neurological deficits in the majority of these patients.

Original languageEnglish (US)
Pages (from-to)490-501
Number of pages12
JournalDevelopmental Medicine and Child Neurology
Volume35
Issue number6
StatePublished - 1993
Externally publishedYes

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Septo-Optic Dysplasia
Septum Pellucidum
Language Development
Optic Nerve
Visual Acuity
Absence of septum pellucidum

ASJC Scopus subject areas

  • Clinical Neurology
  • Pediatrics, Perinatology, and Child Health
  • Neuroscience(all)

Cite this

Williams, J., Brodsky, M. C., Griebel, M., Glasier, C. M., Caldwell, D., & Thomas, P. (1993). Septo-optic dysplasia: The clinical insignificance of an absent septum pellucidum. Developmental Medicine and Child Neurology, 35(6), 490-501.

Septo-optic dysplasia : The clinical insignificance of an absent septum pellucidum. / Williams, J.; Brodsky, Michael C; Griebel, M.; Glasier, C. M.; Caldwell, D.; Thomas, P.

In: Developmental Medicine and Child Neurology, Vol. 35, No. 6, 1993, p. 490-501.

Research output: Contribution to journalArticle

Williams, J, Brodsky, MC, Griebel, M, Glasier, CM, Caldwell, D & Thomas, P 1993, 'Septo-optic dysplasia: The clinical insignificance of an absent septum pellucidum', Developmental Medicine and Child Neurology, vol. 35, no. 6, pp. 490-501.
Williams, J. ; Brodsky, Michael C ; Griebel, M. ; Glasier, C. M. ; Caldwell, D. ; Thomas, P. / Septo-optic dysplasia : The clinical insignificance of an absent septum pellucidum. In: Developmental Medicine and Child Neurology. 1993 ; Vol. 35, No. 6. pp. 490-501.
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