Separation anxiety: Detachment from the extracellular matrix induces metabolic changes that can stimulate tumorigenesis

Magdalena A. Cichon, Derek C. Radisky

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

One of the earliest stages of tumor progression involves the ability of cells to survive and proliferate when not attached to the extracellular matrix (ECM). New research using a physiologically relevant breast cancer model reveals how separation from the ECM stimulates metabolic changes characteristic of developing tumors.

Original languageEnglish (US)
Pages (from-to)113-115
Number of pages3
JournalJournal of Molecular Cell Biology
Volume2
Issue number3
DOIs
StatePublished - Dec 1 2010

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics
  • Cell Biology

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