Semi-quantitative analysis of the bone scan in acromegaly: Correlation with human growth hormone values

I. Fogelman; I. D. Hay; D. L. Citrin; G. H. Beastall; J. G. Turner; R. G. Bessent

doi:10.1259/0007-1285-53-633-874

Semi-quantitative analysis of the bone scan in acromegaly: Correlation with human growth hormone values

I. Fogelman, I. D. Hay, D. L. Citrin, G. H. Beastall, J. G. Turner, R. G. Bessent

Endocrinology, Diabetes, Metabolism, and Nutrition

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

⁹⁹Tc(m)-HEDP bone scans were obtained in 20 acromegalic patients. Twelve patients had active disease with elevated basal serum human growth hormone (HGH) levels. Eight patients were in clinical and biochemical remission. The bone scans, assessed independently by 3 observers, showed features characteristic of metabolic bone disease in patients with active acromegaly. The metabolic index derived from the scan correlated well with serum HGH levels (R = 0.71, p < 0.002). The bone scan may accurately reflect oversecretion of HGH and is of potential value in the assessment of patients with acromegaly.

Original language	English (US)
Pages (from-to)	874-877
Number of pages	4
Journal	British Journal of Radiology
Volume	53
Issue number	633
DOIs	https://doi.org/10.1259/0007-1285-53-633-874
State	Published - 1980

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

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title = "Semi-quantitative analysis of the bone scan in acromegaly: Correlation with human growth hormone values",

abstract = "99Tc(m)-HEDP bone scans were obtained in 20 acromegalic patients. Twelve patients had active disease with elevated basal serum human growth hormone (HGH) levels. Eight patients were in clinical and biochemical remission. The bone scans, assessed independently by 3 observers, showed features characteristic of metabolic bone disease in patients with active acromegaly. The metabolic index derived from the scan correlated well with serum HGH levels (R = 0.71, p < 0.002). The bone scan may accurately reflect oversecretion of HGH and is of potential value in the assessment of patients with acromegaly.",

author = "I. Fogelman and Hay, {I. D.} and Citrin, {D. L.} and Beastall, {G. H.} and Turner, {J. G.} and Bessent, {R. G.}",

year = "1980",

doi = "10.1259/0007-1285-53-633-874",

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T2 - Correlation with human growth hormone values

AU - Fogelman, I.

AU - Hay, I. D.

AU - Citrin, D. L.

AU - Beastall, G. H.

AU - Turner, J. G.

AU - Bessent, R. G.

PY - 1980

Y1 - 1980

N2 - 99Tc(m)-HEDP bone scans were obtained in 20 acromegalic patients. Twelve patients had active disease with elevated basal serum human growth hormone (HGH) levels. Eight patients were in clinical and biochemical remission. The bone scans, assessed independently by 3 observers, showed features characteristic of metabolic bone disease in patients with active acromegaly. The metabolic index derived from the scan correlated well with serum HGH levels (R = 0.71, p < 0.002). The bone scan may accurately reflect oversecretion of HGH and is of potential value in the assessment of patients with acromegaly.

AB - 99Tc(m)-HEDP bone scans were obtained in 20 acromegalic patients. Twelve patients had active disease with elevated basal serum human growth hormone (HGH) levels. Eight patients were in clinical and biochemical remission. The bone scans, assessed independently by 3 observers, showed features characteristic of metabolic bone disease in patients with active acromegaly. The metabolic index derived from the scan correlated well with serum HGH levels (R = 0.71, p < 0.002). The bone scan may accurately reflect oversecretion of HGH and is of potential value in the assessment of patients with acromegaly.

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Semi-quantitative analysis of the bone scan in acromegaly: Correlation with human growth hormone values

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