Semi-quantitative analysis of the bone scan in acromegaly: Correlation with human growth hormone values

I. Fogelman, I. D. Hay, D. L. Citrin, G. H. Beastall, J. G. Turner, R. G. Bessent

Research output: Contribution to journalArticle

2 Scopus citations

Abstract

99Tc(m)-HEDP bone scans were obtained in 20 acromegalic patients. Twelve patients had active disease with elevated basal serum human growth hormone (HGH) levels. Eight patients were in clinical and biochemical remission. The bone scans, assessed independently by 3 observers, showed features characteristic of metabolic bone disease in patients with active acromegaly. The metabolic index derived from the scan correlated well with serum HGH levels (R = 0.71, p < 0.002). The bone scan may accurately reflect oversecretion of HGH and is of potential value in the assessment of patients with acromegaly.

Original languageEnglish (US)
Pages (from-to)874-877
Number of pages4
JournalBritish Journal of Radiology
Volume53
Issue number633
DOIs
StatePublished - Jan 1 1980

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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