Self-Regulatory Fatigue, Quality of Life, Health Behaviors, and Coping in Patients with Hematologic Malignancies

Lise Solberg Nes, Shawna L. Ehlers, Christi A. Patten, Dennis A. Gastineau

Research output: Contribution to journalArticlepeer-review

6 Scopus citations


Background: Self-regulatory fatigue may play an important role in a complex medical illness.

Purpose: Examine associations between self-regulatory fatigue, quality of life, and health behaviors in patients pre- (N = 213) and 1-year post-hematopoietic stem cell transplantation (HSCT; N = 140). Associations between self-regulatory fatigue and coping strategies pre-HSCT were also examined.

Method: Pre- and 1-year post-HSCT data collection. Hierarchical linear regression modeling.

Results: Higher self-regulatory fatigue pre-HSCT associated with lower overall, physical, social, emotional, and functional quality of life pre- (p’s <.001) and 1-year post-HSCT (p’s <.01); lower physical activity pre-HSCT (p <.02) and post-HSCT (p <.03) and less healthy nutritional intake post-HSCT (p <.01); changes (i.e., decrease) in quality of life and healthy nutrition over the follow-up year; and use of avoidance coping strategies pre-HSCT (p’s <.001).

Conclusion: This is the first study to show self-regulatory fatigue pre-HSCT relating to decreased quality of life and health behaviors, and predicting changes in these variables 1-year post-HSCT.

Original languageEnglish (US)
Pages (from-to)411-423
Number of pages13
JournalAnnals of Behavioral Medicine
Issue number3
StatePublished - Dec 2014


  • Coping
  • Health behaviors
  • Hematologic malignancies
  • Hematopoietic stem cell transplantation
  • Quality of life
  • Self-regulatory fatigue

ASJC Scopus subject areas

  • Psychology(all)
  • Psychiatry and Mental health


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