TY - JOUR
T1 - Selection of optimal tube potential settings for dual-energy CT virtual mono-energetic imaging of iodine in the abdomen
AU - Michalak, Gregory
AU - Grimes, Joshua
AU - Fletcher, Joel Garland
AU - Halaweish, Ahmed
AU - Yu, Lifeng
AU - Leng, Shuai
AU - McCollough, Cynthia H
PY - 2017/4/1
Y1 - 2017/4/1
N2 - Abstract: Purpose: To determine the appropriate tube potential settings for dual-source, dual-energy data acquisition across a range of phantom sizes, and to determine the optimal photon energies for virtual mono-energetic imaging. Abstract: Methods: Water phantoms (15–50-cm wide) containing an iodine test object were scanned on a third-generation dual-source CT scanner using all available tube potential pairs. Virtual mono-energetic images at 40, 50, 60, and 70 keV were produced using Mono-energetic Plus. To determine the practical operating parameters for the evaluated CT system, data exclusions were made based on water CT number accuracy, artifacts, and using a noise constraint. Image quality metrics were measured and compared. Abstract: Results: Excluded tube potential pairs were identified; these were generally at low tube potentials for the low-energy beam and low photon energies. For non-excluded conditions, the highest CNR was obtained using the 70/150Sn setting in phantoms ≤35 cm at 40 keV. Abstract: Conclusions: 70/150Sn provided optimal iodine CNR below 40 cm lateral phantom width at 40 keV, while 90/150Sn allowed acceptable image quality in phantoms >40-cm wide at or above 60 keV.
AB - Abstract: Purpose: To determine the appropriate tube potential settings for dual-source, dual-energy data acquisition across a range of phantom sizes, and to determine the optimal photon energies for virtual mono-energetic imaging. Abstract: Methods: Water phantoms (15–50-cm wide) containing an iodine test object were scanned on a third-generation dual-source CT scanner using all available tube potential pairs. Virtual mono-energetic images at 40, 50, 60, and 70 keV were produced using Mono-energetic Plus. To determine the practical operating parameters for the evaluated CT system, data exclusions were made based on water CT number accuracy, artifacts, and using a noise constraint. Image quality metrics were measured and compared. Abstract: Results: Excluded tube potential pairs were identified; these were generally at low tube potentials for the low-energy beam and low photon energies. For non-excluded conditions, the highest CNR was obtained using the 70/150Sn setting in phantoms ≤35 cm at 40 keV. Abstract: Conclusions: 70/150Sn provided optimal iodine CNR below 40 cm lateral phantom width at 40 keV, while 90/150Sn allowed acceptable image quality in phantoms >40-cm wide at or above 60 keV.
KW - Dual-energy CT
KW - Virtual mono-chromatic
KW - Virtual mono-energetic
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U2 - 10.1007/s00261-017-1122-7
DO - 10.1007/s00261-017-1122-7
M3 - Article
C2 - 28365785
AN - SCOPUS:85016472333
SP - 1
EP - 8
JO - Abdominal Radiology
JF - Abdominal Radiology
SN - 2366-004X
ER -