Segmental analysis of sodium reabsorption during renal vein constriction

John C Jr. Burnett, J. A. Haas, F. G. Knox

Research output: Chapter in Book/Report/Conference proceedingChapter

12 Citations (Scopus)

Abstract

Clearance and micropuncture studies were performed in rats to identify the nephron sit(s) of altered sodium reabsorption during partial renal vein constriction in the presence and absence of volume expansion. Renal vein constriction increased fractional delivery of sodium to the late proximal tubule from 52±3 to 61±4% in euvolemia and from 59±3 to 65±3% in volume expansion. In euvolemia, fractional delivery of sodium to the early distal tubule was 13±3% before and 24±6% after renal vein constriction. In volume expansion, fractional delivery of sodium to the early distal tubule decreased from 15±3 to 9±2% in response to renal vein constriction. We conclude that renal vein constriction decreases sodium reabsorption by the proximal tubule both in euvolemia and in volume expansion but that it increases sodium reabsorption by the superficial loop of Henle only in the presence of volume expansion.

Original languageEnglish (US)
Title of host publicationAmerican Journal of Physiology - Renal Fluid and Electrolyte Physiology
Volume12
Edition1
StatePublished - 1982

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Renal Veins
Constriction
Sodium
Loop of Henle
Nephrons
Punctures

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Burnett, J. C. J., Haas, J. A., & Knox, F. G. (1982). Segmental analysis of sodium reabsorption during renal vein constriction. In American Journal of Physiology - Renal Fluid and Electrolyte Physiology (1 ed., Vol. 12)

Segmental analysis of sodium reabsorption during renal vein constriction. / Burnett, John C Jr.; Haas, J. A.; Knox, F. G.

American Journal of Physiology - Renal Fluid and Electrolyte Physiology. Vol. 12 1. ed. 1982.

Research output: Chapter in Book/Report/Conference proceedingChapter

Burnett, JCJ, Haas, JA & Knox, FG 1982, Segmental analysis of sodium reabsorption during renal vein constriction. in American Journal of Physiology - Renal Fluid and Electrolyte Physiology. 1 edn, vol. 12.
Burnett JCJ, Haas JA, Knox FG. Segmental analysis of sodium reabsorption during renal vein constriction. In American Journal of Physiology - Renal Fluid and Electrolyte Physiology. 1 ed. Vol. 12. 1982
Burnett, John C Jr. ; Haas, J. A. ; Knox, F. G. / Segmental analysis of sodium reabsorption during renal vein constriction. American Journal of Physiology - Renal Fluid and Electrolyte Physiology. Vol. 12 1. ed. 1982.
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