In the last five years, bioluminescence has emerged as a vital tool in the non-invasive quantification of β-cell mass following islet transplantation in murine models. The successes achieved in bioluminescence imaging in islet transplantation has prompted its use in the discipline of β-cell regeneration. Employing bioluminescence permits quantifying changes in β-cell mass in an individual mouse over time, which can provide valuable insights into the kinetics of β-cell regeneration.
- (MIP)-luc mouse
- In vivo
- β-cell regeneration
ASJC Scopus subject areas
- Endocrinology, Diabetes and Metabolism