Abstract
In the last five years, bioluminescence has emerged as a vital tool in the non-invasive quantification of β-cell mass following islet transplantation in murine models. The successes achieved in bioluminescence imaging in islet transplantation has prompted its use in the discipline of β-cell regeneration. Employing bioluminescence permits quantifying changes in β-cell mass in an individual mouse over time, which can provide valuable insights into the kinetics of β-cell regeneration.
Original language | English (US) |
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Pages (from-to) | 261-262 |
Number of pages | 2 |
Journal | Islets |
Volume | 2 |
Issue number | 4 |
DOIs | |
State | Published - Jul 2010 |
Keywords
- (MIP)-luc mouse
- Bioluminescence
- In vivo
- Islet
- β-cell regeneration
ASJC Scopus subject areas
- Endocrinology, Diabetes and Metabolism
- Endocrinology