Seeing is believing: How the MIP-luc mouse can advance the field of islet transplantation and β-cell regeneration

Eric Grossman, David Lee, Jing Tao, Raphael Wilson, Soo Young Park, Graeme Bell, Anita Chong

Research output: Contribution to journalReview articlepeer-review

2 Scopus citations

Abstract

In the last five years, bioluminescence has emerged as a vital tool in the non-invasive quantification of β-cell mass following islet transplantation in murine models. The successes achieved in bioluminescence imaging in islet transplantation has prompted its use in the discipline of β-cell regeneration. Employing bioluminescence permits quantifying changes in β-cell mass in an individual mouse over time, which can provide valuable insights into the kinetics of β-cell regeneration.

Original languageEnglish (US)
Pages (from-to)261-262
Number of pages2
JournalIslets
Volume2
Issue number4
DOIs
StatePublished - Jul 1 2010

Keywords

  • (MIP)-luc mouse
  • Bioluminescence
  • In vivo
  • Islet
  • β-cell regeneration

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Endocrinology

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