Screening for Lung Cancer

David E. Midthun

doi:10.1016/j.ccm.2011.08.014

Screening for Lung Cancer

David E. Midthun

Pulmonary and Critical Care Medicine

Research output: Contribution to journal › Review article › peer-review

19 Scopus citations

Abstract

The National Lung Screening Study has demonstrated that screening with low-dose spiral computed tomography results in fewer deaths from lung cancer compared with screening with chest radiography (CXR). Previous trials of screening with CXR and sputum cytology failed to exhibit fewer deaths compared with no screening intervention. Early computed tomography (CT) studies showed promise for CT to be a more sensitive test, yet were unable to demonstrate sufficient evidence of efficacy. This review examines the problem of early lung cancer detection, the issues presented by screening, and results of past and recent studies of lung cancer screening.

Original language	English (US)
Pages (from-to)	659-668
Number of pages	10
Journal	Clinics in Chest Medicine
Volume	32
Issue number	4
DOIs	https://doi.org/10.1016/j.ccm.2011.08.014
State	Published - Dec 2011

Keywords

Computed tomography screening
Mortality reduction
Nodule evaluation
Randomized trials
Screen bias

ASJC Scopus subject areas

Pulmonary and Respiratory Medicine

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10.1016/j.ccm.2011.08.014

Cite this

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title = "Screening for Lung Cancer",

abstract = "The National Lung Screening Study has demonstrated that screening with low-dose spiral computed tomography results in fewer deaths from lung cancer compared with screening with chest radiography (CXR). Previous trials of screening with CXR and sputum cytology failed to exhibit fewer deaths compared with no screening intervention. Early computed tomography (CT) studies showed promise for CT to be a more sensitive test, yet were unable to demonstrate sufficient evidence of efficacy. This review examines the problem of early lung cancer detection, the issues presented by screening, and results of past and recent studies of lung cancer screening.",

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AU - Midthun, David E.

PY - 2011/12

Y1 - 2011/12

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AB - The National Lung Screening Study has demonstrated that screening with low-dose spiral computed tomography results in fewer deaths from lung cancer compared with screening with chest radiography (CXR). Previous trials of screening with CXR and sputum cytology failed to exhibit fewer deaths compared with no screening intervention. Early computed tomography (CT) studies showed promise for CT to be a more sensitive test, yet were unable to demonstrate sufficient evidence of efficacy. This review examines the problem of early lung cancer detection, the issues presented by screening, and results of past and recent studies of lung cancer screening.

KW - Computed tomography screening

KW - Mortality reduction

KW - Nodule evaluation

KW - Randomized trials

KW - Screen bias

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Screening for Lung Cancer

Abstract

Keywords

ASJC Scopus subject areas

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