Screening for bipolar disorders: Clinical utilization of the Mood Disorders Questionnaire on an inpatient mood disorders unit

Simon Kung, Brian A. Palmer, Maria Isabel Lapid, Kathleen A. Poppe, Renato D. Alarcon, Mark A Frye

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Background: The Mood Disorders Questionnaire (MDQ) is a widely used screening instrument for bipolar disorders. The MDQ has seldom been used in the inpatient setting, and we report a clinical, real-world inpatient validation. Methods: Between April 2011 and August 2013, patients admitted to the inpatient Mood Disorders Unit completed an MDQ as part of their admission process. Patients with a discharge diagnosis of unipolar or bipolar disorders were included. The sensitivity and specificity were calculated for each number of questionnaire items checked positive, as well as the symptoms clustered around the same time and with moderate impairment in functioning. Results: A total of 1330 patient MDQ's were identified, and after excluding incomplete MDQ's and non-unipolar or bipolar diagnoses (e.g. anxiety, adjustment, or schizoaffective diagnoses), 860 MDQ's remained. One hundred fifty four patients (18%) were diagnosed with bipolar disorder, and 706 (82%) with unipolar depressive disorder. The average length of stay was 7.6 days. The optimal cutoff score was 8, resulting in a sensitivity/specificity of 86%/71%, compared to 92%/64% with a cutoff of 7. Limitations: Retrospective study using clinical diagnoses instead of research instrument diagnoses. Conclusions: The sensitivity of the MDQ in an inpatient mood disorders setting was higher than an outpatient psychiatric population, but the specificity was lower. A cutoff of 8 instead of the recommended outpatient cutoff of 7 was optimal. In today's busy clinical practices, a screening instrument for bipolar disorder is still useful, and the MDQ can be effectively utilized on an inpatient psychiatry mood disorders unit.

Original languageEnglish (US)
Pages (from-to)97-100
Number of pages4
JournalJournal of Affective Disorders
Volume188
DOIs
StatePublished - Dec 1 2015

Fingerprint

Mood Disorders
Bipolar Disorder
Inpatients
Psychiatry
Outpatients
Social Adjustment
Sensitivity and Specificity
Surveys and Questionnaires
Depressive Disorder
Length of Stay
Anxiety
Retrospective Studies
Research
Population

Keywords

  • Bipolar disorder
  • Inpatient
  • MDQ
  • Mood Disorders Questionnaire
  • Validation

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Clinical Psychology

Cite this

Screening for bipolar disorders : Clinical utilization of the Mood Disorders Questionnaire on an inpatient mood disorders unit. / Kung, Simon; Palmer, Brian A.; Lapid, Maria Isabel; Poppe, Kathleen A.; Alarcon, Renato D.; Frye, Mark A.

In: Journal of Affective Disorders, Vol. 188, 01.12.2015, p. 97-100.

Research output: Contribution to journalArticle

@article{c3c5a4d0586345e9b6e6383a818b1be1,
title = "Screening for bipolar disorders: Clinical utilization of the Mood Disorders Questionnaire on an inpatient mood disorders unit",
abstract = "Background: The Mood Disorders Questionnaire (MDQ) is a widely used screening instrument for bipolar disorders. The MDQ has seldom been used in the inpatient setting, and we report a clinical, real-world inpatient validation. Methods: Between April 2011 and August 2013, patients admitted to the inpatient Mood Disorders Unit completed an MDQ as part of their admission process. Patients with a discharge diagnosis of unipolar or bipolar disorders were included. The sensitivity and specificity were calculated for each number of questionnaire items checked positive, as well as the symptoms clustered around the same time and with moderate impairment in functioning. Results: A total of 1330 patient MDQ's were identified, and after excluding incomplete MDQ's and non-unipolar or bipolar diagnoses (e.g. anxiety, adjustment, or schizoaffective diagnoses), 860 MDQ's remained. One hundred fifty four patients (18{\%}) were diagnosed with bipolar disorder, and 706 (82{\%}) with unipolar depressive disorder. The average length of stay was 7.6 days. The optimal cutoff score was 8, resulting in a sensitivity/specificity of 86{\%}/71{\%}, compared to 92{\%}/64{\%} with a cutoff of 7. Limitations: Retrospective study using clinical diagnoses instead of research instrument diagnoses. Conclusions: The sensitivity of the MDQ in an inpatient mood disorders setting was higher than an outpatient psychiatric population, but the specificity was lower. A cutoff of 8 instead of the recommended outpatient cutoff of 7 was optimal. In today's busy clinical practices, a screening instrument for bipolar disorder is still useful, and the MDQ can be effectively utilized on an inpatient psychiatry mood disorders unit.",
keywords = "Bipolar disorder, Inpatient, MDQ, Mood Disorders Questionnaire, Validation",
author = "Simon Kung and Palmer, {Brian A.} and Lapid, {Maria Isabel} and Poppe, {Kathleen A.} and Alarcon, {Renato D.} and Frye, {Mark A}",
year = "2015",
month = "12",
day = "1",
doi = "10.1016/j.jad.2015.08.060",
language = "English (US)",
volume = "188",
pages = "97--100",
journal = "Journal of Affective Disorders",
issn = "0165-0327",
publisher = "Elsevier",

}

TY - JOUR

T1 - Screening for bipolar disorders

T2 - Clinical utilization of the Mood Disorders Questionnaire on an inpatient mood disorders unit

AU - Kung, Simon

AU - Palmer, Brian A.

AU - Lapid, Maria Isabel

AU - Poppe, Kathleen A.

AU - Alarcon, Renato D.

AU - Frye, Mark A

PY - 2015/12/1

Y1 - 2015/12/1

N2 - Background: The Mood Disorders Questionnaire (MDQ) is a widely used screening instrument for bipolar disorders. The MDQ has seldom been used in the inpatient setting, and we report a clinical, real-world inpatient validation. Methods: Between April 2011 and August 2013, patients admitted to the inpatient Mood Disorders Unit completed an MDQ as part of their admission process. Patients with a discharge diagnosis of unipolar or bipolar disorders were included. The sensitivity and specificity were calculated for each number of questionnaire items checked positive, as well as the symptoms clustered around the same time and with moderate impairment in functioning. Results: A total of 1330 patient MDQ's were identified, and after excluding incomplete MDQ's and non-unipolar or bipolar diagnoses (e.g. anxiety, adjustment, or schizoaffective diagnoses), 860 MDQ's remained. One hundred fifty four patients (18%) were diagnosed with bipolar disorder, and 706 (82%) with unipolar depressive disorder. The average length of stay was 7.6 days. The optimal cutoff score was 8, resulting in a sensitivity/specificity of 86%/71%, compared to 92%/64% with a cutoff of 7. Limitations: Retrospective study using clinical diagnoses instead of research instrument diagnoses. Conclusions: The sensitivity of the MDQ in an inpatient mood disorders setting was higher than an outpatient psychiatric population, but the specificity was lower. A cutoff of 8 instead of the recommended outpatient cutoff of 7 was optimal. In today's busy clinical practices, a screening instrument for bipolar disorder is still useful, and the MDQ can be effectively utilized on an inpatient psychiatry mood disorders unit.

AB - Background: The Mood Disorders Questionnaire (MDQ) is a widely used screening instrument for bipolar disorders. The MDQ has seldom been used in the inpatient setting, and we report a clinical, real-world inpatient validation. Methods: Between April 2011 and August 2013, patients admitted to the inpatient Mood Disorders Unit completed an MDQ as part of their admission process. Patients with a discharge diagnosis of unipolar or bipolar disorders were included. The sensitivity and specificity were calculated for each number of questionnaire items checked positive, as well as the symptoms clustered around the same time and with moderate impairment in functioning. Results: A total of 1330 patient MDQ's were identified, and after excluding incomplete MDQ's and non-unipolar or bipolar diagnoses (e.g. anxiety, adjustment, or schizoaffective diagnoses), 860 MDQ's remained. One hundred fifty four patients (18%) were diagnosed with bipolar disorder, and 706 (82%) with unipolar depressive disorder. The average length of stay was 7.6 days. The optimal cutoff score was 8, resulting in a sensitivity/specificity of 86%/71%, compared to 92%/64% with a cutoff of 7. Limitations: Retrospective study using clinical diagnoses instead of research instrument diagnoses. Conclusions: The sensitivity of the MDQ in an inpatient mood disorders setting was higher than an outpatient psychiatric population, but the specificity was lower. A cutoff of 8 instead of the recommended outpatient cutoff of 7 was optimal. In today's busy clinical practices, a screening instrument for bipolar disorder is still useful, and the MDQ can be effectively utilized on an inpatient psychiatry mood disorders unit.

KW - Bipolar disorder

KW - Inpatient

KW - MDQ

KW - Mood Disorders Questionnaire

KW - Validation

UR - http://www.scopus.com/inward/record.url?scp=84941309173&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84941309173&partnerID=8YFLogxK

U2 - 10.1016/j.jad.2015.08.060

DO - 10.1016/j.jad.2015.08.060

M3 - Article

C2 - 26344754

AN - SCOPUS:84941309173

VL - 188

SP - 97

EP - 100

JO - Journal of Affective Disorders

JF - Journal of Affective Disorders

SN - 0165-0327

ER -