Sclerosing angiomatoid nodular transformation of the spleen: CT, MR, PET, and 99mTc-sulfur colloid SPECT CT findings with gross and histopathological correlation

Curtis Thacker, Ronald Korn, John Millstine, Howard Harvin, Jeffrey A. Van Lier Ribbink, Michael Gotway

Research output: Contribution to journalArticle

35 Citations (Scopus)

Abstract

Sclerosing angiomatoid nodular transformation (SANT) is a benign, proliferative vascular lesion affecting the spleen. Few reports detailing the cross sectional and PET appearance of this lesion are available, and the lesion's behavior with 99mTc-sulfur colloid scintigraphy is previously unreported. Sclerosing nodular transformation of the spleen shows increased tracer accumulation on positron emission tomography, and a central scar-like appearance with an enhancing capsule and radiating septae on CT and MR studies that reflects the gross and histopathological features of the lesion may be visible. An understanding of this pathological finding may allow prospective recognition of the sclerosing nodular transformation of the spleen on cross sectional imaging studies.

Original languageEnglish (US)
Pages (from-to)683-689
Number of pages7
JournalAbdominal Imaging
Volume35
Issue number6
DOIs
StatePublished - Dec 2010
Externally publishedYes

Fingerprint

Colloids
Sulfur
Spleen
Radionuclide Imaging
Positron-Emission Tomography
Capsules
Cicatrix
Blood Vessels
Cross-Sectional Studies
Single Photon Emission Computed Tomography Computed Tomography

Keywords

  • Mass
  • Positron emission tomography
  • Proliferation
  • Sclerosing angiomatoid nodular transformation
  • Spleen
  • Sulfur colloid
  • Vascular lesion

ASJC Scopus subject areas

  • Gastroenterology
  • Urology
  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

Sclerosing angiomatoid nodular transformation of the spleen : CT, MR, PET, and 99mTc-sulfur colloid SPECT CT findings with gross and histopathological correlation. / Thacker, Curtis; Korn, Ronald; Millstine, John; Harvin, Howard; Van Lier Ribbink, Jeffrey A.; Gotway, Michael.

In: Abdominal Imaging, Vol. 35, No. 6, 12.2010, p. 683-689.

Research output: Contribution to journalArticle

Thacker, Curtis ; Korn, Ronald ; Millstine, John ; Harvin, Howard ; Van Lier Ribbink, Jeffrey A. ; Gotway, Michael. / Sclerosing angiomatoid nodular transformation of the spleen : CT, MR, PET, and 99mTc-sulfur colloid SPECT CT findings with gross and histopathological correlation. In: Abdominal Imaging. 2010 ; Vol. 35, No. 6. pp. 683-689.
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