Scientific Advances and New Frontiers in Mesothelioma Therapeutics

Luciano Mutti; Tobias Peikert; Bruce W.S. Robinson; Arnaud Scherpereel; Anne S. Tsao; Marc de Perrot; Gavitt A. Woodard; David M. Jablons; Jacinta Wiens; Fred R. Hirsch; Haining Yang; Michele Carbone; Anish Thomas; Raffit Hassan

doi:10.1016/j.jtho.2018.06.011

Scientific Advances and New Frontiers in Mesothelioma Therapeutics

Luciano Mutti, Tobias Peikert, Bruce W.S. Robinson, Arnaud Scherpereel, Anne S. Tsao, Marc de Perrot, Gavitt A. Woodard, David M. Jablons, Jacinta Wiens, Fred R. Hirsch, Haining Yang, Michele Carbone, Anish Thomas, Raffit Hassan

Pulmonary and Critical Care Medicine

Research output: Contribution to journal › Review article › peer-review

42 Scopus citations

Abstract

Malignant pleural mesothelioma (MPM) is a rare and aggressive cancer that arises from the mesothelial surface of the pleural and peritoneal cavities, the pericardium, and rarely, the tunica vaginalis. The incidence of MPM is expected to increase worldwide in the next two decades. However, even with the use of multimodality treatment, MPM remains challenging to treat, with a 5-year survival rate of less than 5%. The International Association for the Study of Lung Cancer has gathered experts in different areas of mesothelioma research and management to summarize the most significant scientific advances and new frontiers related to mesothelioma therapeutics.

Original language	English (US)
Pages (from-to)	1269-1283
Number of pages	15
Journal	Journal of Thoracic Oncology
Volume	13
Issue number	9
DOIs	https://doi.org/10.1016/j.jtho.2018.06.011
State	Published - Sep 2018

Keywords

Biomarkers
Chemotherapy
Immunotherapy
Malignant pleural mesothelioma
Oncology therapeutics

ASJC Scopus subject areas

Oncology
Pulmonary and Respiratory Medicine

Access to Document

10.1016/j.jtho.2018.06.011

Cite this

Scientific Advances and New Frontiers in Mesothelioma Therapeutics. / Mutti, Luciano; Peikert, Tobias; Robinson, Bruce W.S.; Scherpereel, Arnaud; Tsao, Anne S.; de Perrot, Marc; Woodard, Gavitt A.; Jablons, David M.; Wiens, Jacinta; Hirsch, Fred R.; Yang, Haining; Carbone, Michele; Thomas, Anish; Hassan, Raffit.

In: Journal of Thoracic Oncology, Vol. 13, No. 9, 09.2018, p. 1269-1283.

Research output: Contribution to journal › Review article › peer-review

Mutti, Luciano ; Peikert, Tobias ; Robinson, Bruce W.S. ; Scherpereel, Arnaud ; Tsao, Anne S. ; de Perrot, Marc ; Woodard, Gavitt A. ; Jablons, David M. ; Wiens, Jacinta ; Hirsch, Fred R. ; Yang, Haining ; Carbone, Michele ; Thomas, Anish ; Hassan, Raffit. / Scientific Advances and New Frontiers in Mesothelioma Therapeutics. In: Journal of Thoracic Oncology. 2018 ; Vol. 13, No. 9. pp. 1269-1283.

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abstract = "Malignant pleural mesothelioma (MPM) is a rare and aggressive cancer that arises from the mesothelial surface of the pleural and peritoneal cavities, the pericardium, and rarely, the tunica vaginalis. The incidence of MPM is expected to increase worldwide in the next two decades. However, even with the use of multimodality treatment, MPM remains challenging to treat, with a 5-year survival rate of less than 5%. The International Association for the Study of Lung Cancer has gathered experts in different areas of mesothelioma research and management to summarize the most significant scientific advances and new frontiers related to mesothelioma therapeutics.",

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note = "Funding Information: This work has in part been supported by the Intramural Program of the National Institutes of Health. We than PhD students Emyr Bakker and Alice Guazzelli, and Erina He from the Medical Arts Department, National Institutes of Health, for helping to create Table 1 and Figure 1 . Publisher Copyright: {\textcopyright} 2018",

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AU - Carbone, Michele

AU - Thomas, Anish

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Scientific Advances and New Frontiers in Mesothelioma Therapeutics

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Keywords

ASJC Scopus subject areas

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