Science to practice: Will inversion recovery with on-resonant water suppression be another way to routinely exploit off-resonance effects with MR imaging?

In this issue of Radiology, Korosoglou et al (1) evaluated the utility of inversion recovery with on-resonant water suppression (IRON) in combination with injection of the long-circulating monocrystalline iron oxide nanoparticle-47 for contrast material-enhanced magnetic resonance (MR) angiography. They found that IRON MR angiography in conjunction with superparamagnetic nanoparticle administration provided high intravascular contrast over a long time and without the need for image subtraction.