Schwarz meets schwann: Design and fabrication of biomorphic tissue engineering scaffolds

Srinivasan Rajagopalan, Richard A. Robb

Research output: Chapter in Book/Report/Conference proceedingConference contribution

6 Scopus citations

Abstract

Tissue engineering is a discipline at the leading edge of the field of computer assisted intervention. This multidisciplinary engineering science is based on the notion of design and fabrication of scaffolds- porous, threedimensional "trellis-like" biomimetic structures that, on implantation, provide a viable environment to recuperate and regenerate damaged cells. Existing CADbased approaches produce porous labyrinths with contra-naturam straight edges. The biomorphic geometry that mimics the secundam-naturam substrate would be one that is continuous through all space, partitioned into two notnecessarily-equal sub-spaces by a non-intersecting, two-sided surface. Minimal surfaces are ideal to describe such a space. We present results on the premier attempt in computer controlled fabrication and mechanical characterization of Triply Periodic Minimal Surfaces [TPMS], This initiative is a significant step to link Schwann's 1838 cell theory with Schwarz's discovery of TPMS in 1865 to fabricate the previously elusive optimal biomorphic tissue analogs.

Original languageEnglish (US)
Title of host publicationMedical Image Computing and Computer-Assisted Intervention - MICCAI 2005 - 8th International Conference, Proceedings
Pages794-801
Number of pages8
DOIs
StatePublished - Dec 1 2005
Event8th International Conference on Medical Image Computing and Computer-Assisted Intervention - MICCAI 2005 - Palm Springs, CA, United States
Duration: Oct 26 2005Oct 29 2005

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume3749 LNCS
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349

Other

Other8th International Conference on Medical Image Computing and Computer-Assisted Intervention - MICCAI 2005
CountryUnited States
CityPalm Springs, CA
Period10/26/0510/29/05

ASJC Scopus subject areas

  • Theoretical Computer Science
  • Computer Science(all)

Fingerprint Dive into the research topics of 'Schwarz meets schwann: Design and fabrication of biomorphic tissue engineering scaffolds'. Together they form a unique fingerprint.

  • Cite this

    Rajagopalan, S., & Robb, R. A. (2005). Schwarz meets schwann: Design and fabrication of biomorphic tissue engineering scaffolds. In Medical Image Computing and Computer-Assisted Intervention - MICCAI 2005 - 8th International Conference, Proceedings (pp. 794-801). (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); Vol. 3749 LNCS). https://doi.org/10.1007/11566465_98