Scalp-recorded EEG localization in MRI volume data

Benjamin Brinkmann, Terence J. O'Brien, M. Alex Dresner, Terrence D. Lagerlund, Frank W. Sharbrough, Richard A. Robb

Research output: Contribution to journalArticle

33 Citations (Scopus)

Abstract

Scalp-recorded EEG is a noninvasive and widely available tool for studying normal and dysfunctional human neurophysiology with unsurpassed temporal resolution. However, scalp-recorded EEG data is difficult to correlate with anatomy, and most current display and neural source estimation algorithms are based on unrealistic spherical or elliptical models of the head. It is possible to measure the positions of electrodes on the patient's scalp, and to register those electrode positions into the space of a high-resolution MRI volume, and to then use the patient-specific anatomy as the basis for display and estimation of neural sources. We use a surface matching algorithm to register digitized electrode and scalp surface coordinates to a three-dimensional MRI volume. This study uses fiducial markers in phantom and volunteer studies to quantitatively estimate the accuracy of the electrode registration method. Our electrode registration procedure is accurate to 2.21 mm for a realistic head phantom and accurate to 4.16 mm on average for five volunteers. This level of accuracy is considered within acceptable limits for clinical applications.

Original languageEnglish (US)
Pages (from-to)245-253
Number of pages9
JournalBrain Topography
Volume10
Issue number4
DOIs
StatePublished - 1998

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Scalp
Electroencephalography
Electrodes
Volunteers
Anatomy
Head
Fiducial Markers
Neurophysiology

Keywords

  • Electroencephalography (EEG)
  • Focal epilepsy
  • Magnetic resonance imaging (MRI)
  • Registration

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

Cite this

Brinkmann, B., O'Brien, T. J., Dresner, M. A., Lagerlund, T. D., Sharbrough, F. W., & Robb, R. A. (1998). Scalp-recorded EEG localization in MRI volume data. Brain Topography, 10(4), 245-253. https://doi.org/10.1023/A:1022266822252

Scalp-recorded EEG localization in MRI volume data. / Brinkmann, Benjamin; O'Brien, Terence J.; Dresner, M. Alex; Lagerlund, Terrence D.; Sharbrough, Frank W.; Robb, Richard A.

In: Brain Topography, Vol. 10, No. 4, 1998, p. 245-253.

Research output: Contribution to journalArticle

Brinkmann, B, O'Brien, TJ, Dresner, MA, Lagerlund, TD, Sharbrough, FW & Robb, RA 1998, 'Scalp-recorded EEG localization in MRI volume data', Brain Topography, vol. 10, no. 4, pp. 245-253. https://doi.org/10.1023/A:1022266822252
Brinkmann B, O'Brien TJ, Dresner MA, Lagerlund TD, Sharbrough FW, Robb RA. Scalp-recorded EEG localization in MRI volume data. Brain Topography. 1998;10(4):245-253. https://doi.org/10.1023/A:1022266822252
Brinkmann, Benjamin ; O'Brien, Terence J. ; Dresner, M. Alex ; Lagerlund, Terrence D. ; Sharbrough, Frank W. ; Robb, Richard A. / Scalp-recorded EEG localization in MRI volume data. In: Brain Topography. 1998 ; Vol. 10, No. 4. pp. 245-253.
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