Salivary Gland Involvement in Wegener's Granulomatosis

Ulrich Specks, Thomas V. Colby, Kerry D. Olsen, Richard A. DeRemee

Research output: Contribution to journalArticle

43 Scopus citations

Abstract

Salivary gland involvement is a rare clinical feature of Wegener's granulomatosis. We report a series of five cases in which submandibular or parotid gland swelling was part of the initial manifestation of the disease. All patients had limited forms of Wegener's granulomatosis. The value of determination of serum anti-neutrophil cytoplasmic autoantibodies is demonstrated in four of the cases, and its use as a new diagnostic adjunct and promising tool to monitor disease activity is discussed. The use of trimethoprim-sulfamethoxazole as part of alternative treatment regimens for limited Wegener's granulomatosis is advocated.

Original languageEnglish (US)
Pages (from-to)218-223
Number of pages6
JournalArchives of Otolaryngology--Head and Neck Surgery
Volume117
Issue number2
DOIs
StatePublished - Feb 1991

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ASJC Scopus subject areas

  • Surgery
  • Otorhinolaryngology

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