Safety and Efficacy of Totally Percutaneous Femoral Access for Fenestrated–Branched Endovascular Aortic Repair of Pararenal–Thoracoabdominal Aortic Aneurysms

Mario D’Oria, Gustavo S. Oderich, Emanuel R. Tenorio, Jussi M. Kärkkäinen, Bernardo C. Mendes, Randall R. DeMartino

Research output: Contribution to journalArticle

2 Scopus citations

Abstract

Introduction: We sought to evaluate the safety and efficacy of totally percutaneous femoral access (TPFA) for fenestrated–branched endovascular aortic repair (F/B-EVAR) of pararenal–thoracoabdominal aortic aneurysms (PRAs/TAAAs). Methods: We reviewed all consecutive patients enrolled in single-center prospective non-randomized single-arm study to investigate F/B-EVAR for PRAs/TAAAs (2013–2017). Percutaneous approach was selected in all patients when anatomically feasible; otherwise, surgical femoral access (SFA), with or without construction of temporary prosthetic conduit, was selected. Primary outcomes were technical success, mortality, major adverse events (MAEs) and major vascular access complications. Results: A total of 231 patients were included in the study: TPFA was possible in 163 (70%) with technical success rate of 93%, while 68 (30%) required SFA. Patients with TPFA and SFA had similar mortality rate of 1%. The rate of MAEs for TPFA was 20% versus 38% for SFA (p =.07). The trend was mainly driven by reduced rates of estimated blood loss (EBL) ≥ 1L (6% vs 21%, p =.001) and acute myocardial infarction (2% vs 9%, p =.03). Similarly, TPFA carried a significantly lower rate of major vascular access complications as compared with SFA (6% vs 21%, p <.001; adjusted OR 3.4, 95% CI 1.3–8.9, p =.01). Conclusion: A percutaneous-first approach for elective F/B-EVAR of PRAs/TAAAs is safe, feasible and effective when proper patient selection is provided. When the presence of hostile iliofemoral anatomy requires open-vessel exposure, higher rates of perioperative major bleeding, cardiac events and access complications may be expected. Level of Evidence: Level 3 (single-center prospective non-randomized single-arm study).

Original languageEnglish (US)
JournalCardioVascular and Interventional Radiology
DOIs
StateAccepted/In press - Jan 1 2020

Keywords

  • Fenestrated and branched endovascular aortic repair
  • Pararenal aortic aneurysms
  • Percutaneous access
  • Thoracoabdominal aortic aneurysms
  • Vascular closure device

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

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