Abstract
The burden of comorbid diseases is high among patients with rheumatoid arthritis (RA). These are often systemic manifestations of RA but may be chronic conditions that predate or develop post-RA diagnosis. Increased mortality in RA is predominantly from nonarticular causes. The expanded armamentarium of disease-modifying drugs and biologics available has revolutionized management of articular disease but has made safe treatment of RA more complex. Drug-induced organ injury and side effects need to be kept in mind when initiating or modifying therapy.
Original language | English (US) |
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Pages (from-to) | 771-793 |
Number of pages | 23 |
Journal | Rheumatic Disease Clinics of North America |
Volume | 38 |
Issue number | 4 |
DOIs | |
State | Published - Nov 2012 |
Keywords
- Adverse drug effects
- Comorbidties
- Disease-modifying antirheumatic drugs
- Rheumatoid arthritis
- Treatment
ASJC Scopus subject areas
- Rheumatology